diff --git a/rotate_backups_s3/__init__.py b/rotate_backups_s3/__init__.py
index be4aad4..14ce5e8 100644
--- a/rotate_backups_s3/__init__.py
+++ b/rotate_backups_s3/__init__.py
@@ -117,7 +117,7 @@ def __init__(self, rotation_scheme, aws_access_key_id, aws_secret_access_key,
             include_list=include_list, exclude_list=exclude_list,
             dry_run=dry_run, config_file=config_file)
 
-    def rotate_backups(self, bucketname):
+    def rotate_backups(self, bucketname, prefix):
         """
         Rotate the backups in a bucket according to a flexible rotation scheme.
 
@@ -126,7 +126,7 @@ def rotate_backups(self, bucketname):
 
         bucket = self.conn.get_bucket(bucketname)
         # Collect the backups in the given directory.
-        sorted_backups = self.collect_backups(bucketname)
+        sorted_backups = self.collect_backups(bucketname, prefix)
         if not sorted_backups:
             logger.info("No backups found in %s.", bucketname)
             return
@@ -157,7 +157,7 @@ def rotate_backups(self, bucketname):
         if len(backups_to_preserve) == len(sorted_backups):
             logger.info("Nothing to do! (all backups preserved)")
 
-    def collect_backups(self, bucketname):
+    def collect_backups(self, bucketname, prefix):
         """
         Collect the backups in the given s3 bucket.
 
@@ -168,9 +168,10 @@ def collect_backups(self, bucketname):
         backups = []
         
         bucket = self.conn.get_bucket(bucketname)
-        logger.info("Scanning bucket for backups: %s", bucketname)
-        
-        for entry in natsort([key.name for key in bucket.list()]):
+
+        logger.info("Scanning for backups: s3://%s/%s", bucketname, prefix)
+
+        for entry in natsort([key.name for key in bucket.list(prefix)]):
             # Check for a time stamp in the directory entry's name.
             match = TIMESTAMP_PATTERN.search(entry)
             if match:
diff --git a/rotate_backups_s3/cli.py b/rotate_backups_s3/cli.py
index e6083eb..fae5e67 100644
--- a/rotate_backups_s3/cli.py
+++ b/rotate_backups_s3/cli.py
@@ -5,7 +5,7 @@
 # URL: https://github.com/xolox/python-rotate-backups
 
 """
-Usage: rotate-backups-s3 [OPTIONS] DIRECTORY..
+Usage: rotate-backups-s3 [OPTIONS] [s3://]bucket[/prefix]..
 
 Easy rotation of backups in an AWS S3 bucket based. To use
 this program you specify a rotation scheme via (a combination of) the --hourly,
@@ -169,7 +169,7 @@ def main():
         # If no arguments are given but the system has a configuration file
         # then the backups in the configured directories are rotated.
         if not arguments:
-            arguments.extend(bucket for bucket, _, _ in load_config_file(config_file))
+            arguments.extend(s3path for s3path, _, _ in load_config_file(config_file))
         # Show the usage message when no directories are given nor configured.
         if not arguments:
             usage(__doc__)
@@ -178,7 +178,15 @@ def main():
         logger.error("%s", e)
         sys.exit(1)
     # Rotate the backups in the given or configured directories.
-    for bucket in arguments:
+    for s3path in arguments:
+        prefix = ''
+        bucket = s3path[5:] if s3path.startswith('s3://') else s3path
+
+        pos = bucket.find('/')
+        if pos != -1:
+            prefix = bucket[pos:].strip('/')
+            bucket = bucket[:pos]
+
         S3RotateBackups(
             rotation_scheme=rotation_scheme,
             aws_access_key_id=aws_access_key_id,
@@ -186,7 +194,7 @@ def main():
             include_list=include_list,
             exclude_list=exclude_list,
             dry_run=dry_run,
-        ).rotate_backups(bucket)
+        ).rotate_backups(bucket, prefix)
 
 if __name__ == "__main__":
     main()
\ No newline at end of file