Main function for retinal vessel segmentation.
result = VesselSegment(imageFile, varargin)Parameters:
imageFile(string): Path to retinal fundus imagemethod(optional): Segmentation method ('rf', 'multiscale', 'hybrid')threshold(optional): Threshold value for binary segmentation
Returns:
result(struct): Segmentation results with fields:segmentation: Binary vessel maskprobability: Probability mapfeatures: Extracted featuresmetrics: Performance metrics (if ground truth available)
Batch processing function for multiple images.
results = multi_test(dataset, method)Parameters:
dataset(string): Dataset name ('DRIVE', 'STARE', 'CHASEDB1')method(string): Segmentation method
Returns:
results(cell): Array of segmentation results
Extract standard features from retinal images.
features = extractFeature(image, mask)Parameters:
image(uint8): RGB retinal imagemask(optional): Region of interest mask
Returns:
features(double): Feature vector
Extract hierarchical features using Local Haar Patterns.
featuresH = extractFeatureH(image, patchSize)Parameters:
image(uint8): RGB retinal imagepatchSize(int): Size of local patches
Returns:
featuresH(double): Hierarchical feature descriptors
Train Random Forest classifier for vessel segmentation.
model = trainRFC(trainingPath, groundTruthPath, options)Parameters:
trainingPath(string): Path to training imagesgroundTruthPath(string): Path to ground truth masksoptions(struct): Training optionsnumTrees: Number of trees (default: 100)maxDepth: Maximum tree depth (default: 10)
Returns:
model(struct): Trained Random Forest model
Test Random Forest classifier on new images.
predictions = testRFC(model, testPath)Parameters:
model(struct): Trained Random Forest modeltestPath(string): Path to test images
Returns:
predictions(cell): Segmentation predictions
Multi-scale line detection for vessel enhancement.
response = get_lineresponse(image, scales, options)Parameters:
image(double): Grayscale retinal imagescales(vector): Scale values for line detectionoptions(struct): Detection options
Returns:
response(double): Line response at multiple scales
Generate binary vessel mask from line response.
mask = get_linemask(response, threshold)Parameters:
response(double): Line response imagethreshold(double): Threshold value
Returns:
mask(logical): Binary vessel mask
Standardize retinal image intensities.
standardImage = standardize(image, method)Parameters:
image(uint8): Input retinal imagemethod(string): Standardization method ('histogram', 'zscore')
Returns:
standardImage(double): Standardized image
Apply noise filtering to retinal images.
filteredImage = noisefiltering(image, filterType)Parameters:
image(uint8): Noisy retinal imagefilterType(string): Filter type ('gaussian', 'median', 'bilateral')
Returns:
filteredImage(uint8): Filtered image
Add padding to images for boundary handling.
paddedImage = fakepad(image, padSize, method)Parameters:
image(numeric): Input imagepadSize(int): Padding sizemethod(string): Padding method ('symmetric', 'replicate')
Returns:
paddedImage(numeric): Padded image
Calculate segmentation accuracy metrics.
metrics = accuracy_tesst(prediction, groundTruth, mask)Parameters:
prediction(logical): Predicted vessel maskgroundTruth(logical): Ground truth vessel maskmask(optional): Field of view mask
Returns:
metrics(struct): Accuracy metricsaccuracy: Overall accuracysensitivity: Sensitivity (recall)specificity: Specificityprecision: Precisionf1Score: F1-scoreauc: Area under ROC curve
Add all necessary paths for the project.
addPaths()Description: Automatically adds all source code directories to MATLAB path.
Create binary descriptors for vessel detection.
descriptors = create_binary(image, keypoints)Parameters:
image(uint8): Retinal imagekeypoints(struct): Detected keypoints
Returns:
descriptors(logical): Binary descriptors
Create 32-bit binary descriptors.
descriptors32 = create_binary_32(image, keypoints)Parameters:
image(uint8): Retinal imagekeypoints(struct): Detected keypoints
Returns:
descriptors32(uint32): 32-bit binary descriptors
Create custom descriptors for vessel characterization.
descriptors = create_descriptor(image, method, parameters)Parameters:
image(uint8): Retinal imagemethod(string): Descriptor type ('lbp', 'glcm', 'gabor')parameters(struct): Method-specific parameters
Returns:
descriptors(double): Feature descriptors
All functions include comprehensive error checking:
try
result = VesselSegment('invalid_path.jpg');
catch ME
switch ME.identifier
case 'VesselSegment:FileNotFound'
fprintf('Error: Image file not found\n');
case 'VesselSegment:InvalidFormat'
fprintf('Error: Unsupported image format\n');
otherwise
rethrow(ME);
end
end- Large images may require processing in patches
- Use
clearcommand to free memory between operations - Monitor memory usage with
memorycommand
- Multi-scale operations are computationally intensive
- Consider parallel processing for batch operations
- Use appropriate image scaling for faster processing
% Efficient batch processing
parfor i = 1:length(imageList)
results{i} = VesselSegment(imageList{i});
end
% Memory-efficient processing
for i = 1:length(imageList)
result = VesselSegment(imageList{i});
save(['result_' num2str(i) '.mat'], 'result');
clear result; % Free memory
end