diff --git a/scrapy_poet/_request_fingerprinter.py b/scrapy_poet/_request_fingerprinter.py
index c5223043..9b9cbdac 100644
--- a/scrapy_poet/_request_fingerprinter.py
+++ b/scrapy_poet/_request_fingerprinter.py
@@ -1,15 +1,15 @@
-from typing import TYPE_CHECKING
-
 try:
     from scrapy.utils.request import RequestFingerprinter  # NOQA
 except ImportError:
+    from typing import TYPE_CHECKING
+
     if not TYPE_CHECKING:
         ScrapyPoetRequestFingerprinter = None
 else:
     import hashlib
     import json
     from functools import cached_property
-    from typing import Callable, Dict, List, Optional
+    from typing import Callable, Dict, List, Optional, get_args, get_origin
     from weakref import WeakKeyDictionary
 
     from scrapy import Request
@@ -20,6 +20,17 @@
     from scrapy_poet import InjectionMiddleware
     from scrapy_poet.injection import get_callback
 
+    def _serialize_dep(cls):
+        try:
+            from typing import Annotated
+        except ImportError:
+            pass
+        else:
+            if get_origin(cls) is Annotated:
+                annotated, *annotations = get_args(cls)
+                return f"{_serialize_dep(annotated)}{repr(annotations)}"
+        return f"{cls.__module__}.{cls.__qualname__}"
+
     class ScrapyPoetRequestFingerprinter:
         @classmethod
         def from_crawler(cls, crawler):
@@ -62,7 +73,7 @@ def _get_deps(self, request: Request) -> Optional[List[str]]:
             root_deps = plan[-1][1]
             if not root_deps:
                 return None
-            return sorted([repr(cls) for cls in root_deps.values()])
+            return sorted([_serialize_dep(cls) for cls in root_deps.values()])
 
         def fingerprint_deps(self, request: Request) -> Optional[bytes]:
             """Return a fingerprint based on dependencies requested through
diff --git a/tests/test_request_fingerprinter.py b/tests/test_request_fingerprinter.py
index 35f3cb5c..61f6af9d 100644
--- a/tests/test_request_fingerprinter.py
+++ b/tests/test_request_fingerprinter.py
@@ -15,6 +15,7 @@
 from web_poet import HttpResponse, ItemPage, PageParams, RequestUrl, WebPage
 
 from scrapy_poet import DummyResponse, ScrapyPoetRequestFingerprinter
+from scrapy_poet._request_fingerprinter import _serialize_dep
 from scrapy_poet.utils.testing import get_crawler as _get_crawler
 
 ANDI_VERSION = Version(package_version("andi"))
@@ -233,6 +234,22 @@ async def parse_b(self, response, b: Annotated[WebPage, "b"]):
     assert fingerprint1 != fingerprint2
 
 
+def test_serialize_dep():
+    assert _serialize_dep(HttpResponse) == "web_poet.page_inputs.http.HttpResponse"
+
+
+@pytest.mark.skipif(
+    sys.version_info < (3, 9), reason="No Annotated support in Python < 3.9"
+)
+def test_serialize_dep_annotated():
+    from typing import Annotated
+
+    assert (
+        _serialize_dep(Annotated[HttpResponse, "foo"])
+        == "web_poet.page_inputs.http.HttpResponse['foo']"
+    )
+
+
 def test_base_default():
     class TestSpider(Spider):
         name = "test_spider"