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1 file changed +6
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lines changed Original file line number Diff line number Diff line change @@ -72,18 +72,21 @@ Site filters (select subset of genomic sites from INDIR):
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2 ) Quantify between-sample heterogenity genome-wide
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` snp_diversity.py /path/to/snps --genomic_type genome-wide --sample_type pooled-sample --out /path/to/output `
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- 3 ) Quantify between-sample heterogenity per-gene
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+ 3 ) Quantify between-sample heterogenity per-gene
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` snp_diversity.py /path/to/snps --genomic_type per-gene --sample_type pooled-samples --out /path/to/output `
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4 ) Use downsampling to control the read-depth at each genomic site
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` snp_diversity.py /path/to/snps --genomic_type genome-wide --sample_type per-sample --out /path/to/output `
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5 ) Only quantify diversity at non-synonymous sites
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+ ` snp_diversity.py /path/to/snps --genomic_type genome-wide --sample_type pooled-samples --site_type 1D --locus_type CDS --out /path/to/output `
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+ 6 ) Only quantify diversity at synonymous sites (Note: use the ratio of 5/6 for pN/pS)
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` snp_diversity.py /path/to/snps --genomic_type genome-wide --sample_type pooled-samples --site_type 4D --locus_type CDS --out /path/to/output `
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- 6 ) Quantify SNPs using a different definition of a polymorphism
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+ 7 ) Quantify SNPs using a different definition of a polymorphism
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` snp_diversity.py /path/to/snps --genomic_type genome-wide --sample_type per-sample --snp_maf 0.05 --out /path/to/output `
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- 7 ) Run a quick test
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+ 8 ) Run a quick test
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` snp_diversity.py /path/to/snps --max_sites 10000 --out /path/to/output `
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