diff --git a/tests/arp/arp_utils.py b/tests/arp/arp_utils.py
index 3b4c73270a6..de6504a6b4b 100644
--- a/tests/arp/arp_utils.py
+++ b/tests/arp/arp_utils.py
@@ -10,11 +10,12 @@
 BASE_MAC_PREFIX = "00:00:01"
 
 
-def clear_dut_arp_cache(duthost, ns_option=None):
+def clear_dut_arp_cache(duthost, ns_option=None, is_ipv6=False):
     logger.info("Clearing {} neighbor table".format(duthost.hostname))
-    arp_flush_cmd = "ip -stats neigh flush all"
+    ipv6_cmd = '-6' if is_ipv6 else ''
+    arp_flush_cmd = "ip {} -stats neigh flush all".format(ipv6_cmd)
     if ns_option:
-        arp_flush_cmd = "ip -stats {} neigh flush all".format(ns_option)
+        arp_flush_cmd = "ip {} -stats {} neigh flush all".format(ipv6_cmd, ns_option)
     duthost.shell(arp_flush_cmd)
 
 
diff --git a/tests/arp/test_stress_arp.py b/tests/arp/test_stress_arp.py
index a5253aa123f..61ced3ad495 100644
--- a/tests/arp/test_stress_arp.py
+++ b/tests/arp/test_stress_arp.py
@@ -9,7 +9,7 @@
 from scapy.all import Ether, IPv6, ICMPv6ND_NS, ICMPv6NDOptSrcLLAddr, in6_getnsmac, \
                       in6_getnsma, inet_pton, inet_ntop, socket
 from ipaddress import ip_address, ip_network
-from tests.common.utilities import wait_until, increment_ipv6_addr
+from tests.common.utilities import wait_until, increment_ipv6_addr, is_ipv6_only_topology
 from tests.common.errors import RunAnsibleModuleFail
 
 
@@ -37,9 +37,10 @@
 
 @pytest.fixture(autouse=True)
 def arp_cache_fdb_cleanup(duthosts, rand_one_dut_hostname, tbinfo):
+    is_ipv6_only = is_ipv6_only_topology(tbinfo)
     duthost = duthosts[rand_one_dut_hostname]
     try:
-        clear_dut_arp_cache(duthost)
+        clear_dut_arp_cache(duthost, is_ipv6=is_ipv6_only)
         fdb_cleanup(duthost)
     except RunAnsibleModuleFail as e:
         if 'Failed to send flush request: No such file or directory' in str(e):
@@ -55,7 +56,7 @@ def arp_cache_fdb_cleanup(duthosts, rand_one_dut_hostname, tbinfo):
     try:
         dut_list = duthosts if "dualtor-aa" in tbinfo["topo"]["name"] else [duthost]
         for dut in dut_list:
-            clear_dut_arp_cache(dut)
+            clear_dut_arp_cache(dut, is_ipv6=is_ipv6_only)
             fdb_cleanup(dut)
     except RunAnsibleModuleFail as e:
         if 'Failed to send flush request: No such file or directory' in str(e):
@@ -112,7 +113,6 @@ def test_ipv4_arp(duthosts, enum_rand_one_per_hwsku_frontend_hostname,
     pytest_assert(ipv4_available > 0 and fdb_available > 0, "Entries have been filled")
 
     arp_available = min(min(ipv4_available, fdb_available), ENTRIES_NUMBERS)
-    # Neighbor support is dependant on NH scale  for some cisco platforms.
     # Limit ARP scale based on available NH entries
     asic_type = duthost.facts["asic_type"]
     if 'cisco-8000' in asic_type:
@@ -197,6 +197,7 @@ def test_ipv6_nd(duthosts, enum_rand_one_per_hwsku_frontend_hostname,
                  ptfhost, config_facts, tbinfo, ip_and_intf_info,
                  ptfadapter, get_function_completeness_level, proxy_arp_enabled):
     duthost = duthosts[enum_rand_one_per_hwsku_frontend_hostname]
+    is_ipv6_only = is_ipv6_only_topology(tbinfo)
     _, _, ptf_intf_ipv6_addr, _, ptf_intf_index = ip_and_intf_info
     ptf_intf_ipv6_addr = increment_ipv6_addr(ptf_intf_ipv6_addr)
     pytest_require(proxy_arp_enabled, 'Proxy ARP not enabled for all VLANs')
@@ -230,7 +231,7 @@ def test_ipv6_nd(duthosts, enum_rand_one_per_hwsku_frontend_hostname,
                               "Neighbor Table Add failed")
         finally:
             try:
-                clear_dut_arp_cache(duthost)
+                clear_dut_arp_cache(duthost, is_ipv6=is_ipv6_only)
                 fdb_cleanup(duthost)
             except RunAnsibleModuleFail as e:
                 if 'Failed to send flush request: No such file or directory' in str(e):
@@ -259,12 +260,11 @@ def send_ipv6_echo_request(ptfadapter, dut_mac, ip_and_intf_info, ptf_intf_index
         testutils.send_packet(ptfadapter, ptf_intf_index, er_pkt)
 
 
-def test_ipv6_nd_incomplete(duthosts, enum_rand_one_per_hwsku_frontend_hostname,
-                            ptfhost, config_facts, tbinfo, ip_and_intf_info,
+def test_ipv6_nd_incomplete(duthost, ptfhost, config_facts, tbinfo, ip_and_intf_info,
                             ptfadapter, get_function_completeness_level, proxy_arp_enabled):
-    duthost = duthosts[enum_rand_one_per_hwsku_frontend_hostname]
     _, _, ptf_intf_ipv6_addr, _, ptf_intf_index = ip_and_intf_info
     ptf_intf_ipv6_addr = increment_ipv6_addr(ptf_intf_ipv6_addr)
+    is_ipv6_only = is_ipv6_only_topology(tbinfo)
     pytest_require(proxy_arp_enabled, 'Proxy ARP not enabled for all VLANs')
     pytest_require(ptf_intf_ipv6_addr is not None, 'No IPv6 VLAN address configured on device')
 
@@ -291,7 +291,7 @@ def test_ipv6_nd_incomplete(duthosts, enum_rand_one_per_hwsku_frontend_hostname,
     logger.info("original nf_conntrack_icmpv6_timeout: {}".format(orig_conntrack_icmpv6_timeout))
 
     try:
-        clear_dut_arp_cache(duthost)
+        clear_dut_arp_cache(duthost, is_ipv6=is_ipv6_only)
 
         duthost.command("conntrack -F")
 
@@ -321,4 +321,4 @@ def test_ipv6_nd_incomplete(duthosts, enum_rand_one_per_hwsku_frontend_hostname,
 
         duthost.command("conntrack -F")
 
-        clear_dut_arp_cache(duthost)
+        clear_dut_arp_cache(duthost, is_ipv6=is_ipv6_only)
diff --git a/tests/common/plugins/conditional_mark/tests_mark_conditions.yaml b/tests/common/plugins/conditional_mark/tests_mark_conditions.yaml
index c2ef7332849..317d91019c2 100644
--- a/tests/common/plugins/conditional_mark/tests_mark_conditions.yaml
+++ b/tests/common/plugins/conditional_mark/tests_mark_conditions.yaml
@@ -128,6 +128,12 @@ arp/test_neighbor_mac_noptf.py:
     conditions:
       - "'standalone' in topo_name"
 
+arp/test_stress_arp.py::test_ipv4_arp:
+  xfail:
+    reason: "skip for IPv6-only topologies"
+    conditions:
+      - "'-v6-' in topo_name"
+
 arp/test_unknown_mac.py:
   skip:
     reason: "Behavior on cisco-8000 & (Marvell) platform for unknown MAC is flooding rather than DROP, hence skipping."