You signed in with another tab or window. Reload to refresh your session.You signed out in another tab or window. Reload to refresh your session.You switched accounts on another tab or window. Reload to refresh your session.Dismiss alert
Copy file name to clipboardExpand all lines: README.md
+10-3Lines changed: 10 additions & 3 deletions
Original file line number
Diff line number
Diff line change
@@ -13,11 +13,18 @@ Starting with **release 2.0.0** (2022-11-20), a **concatenation-independent spec
13
13
**Release 2.1.0** (2024-03-31) implemented the **maximal matched-pairs tests** to asses violations of the data to the Stationarity, Reversibility, and Homogeneity (SRH) assumptions made by maximum-likelihood phylogenetic models, as implemented in [IQ-TREE](http://www.iqtree.org/). In addition, [**ASTRAL-IV**](https://github.com/chaoszhang/ASTER/blob/master/tutorial/astral4.md) is used to estimate the species tree directly from the filtered ML source gene trees, which computes terminal and internal branch lengths in substitution-per-site units.
14
14
15
15
[**Release 2.2.0** (v2.2.0, 2024-04-14)](https://github.com/vinuesa/get_phylomarkers/releases/tag/2.2.0) contains new features, significant code improvements, binary updates, and some bug fixes. Among the new features, we would like to highlight the following ones:
16
+
16
17
-significant extension of run mode 2 (<code>run_get_phylomarkers_pipeline.sh -R 2</code>) for **population genetics** (multiple sequences from the same species):
17
-
- <code>run_get_phylomarkers_pipeline.sh</code> now also calls the C binary [**WEIGHTED-ASTRAL**](https://github.com/chaoszhang/ASTER) to estimate a species tree using as input the filtered gene trees estimated by [iqtree2](http://www.iqtree.org/) or [FastTree](http://www.microbesonline.org/fasttree/) from the core-genome clusters computed by [get_homologues](https://github.com/eead-csic-compbio/get_homologues).
18
-
- The main script <code>run_get_phylomarkers_pipeline.sh</code> added complex protein mixture models for concatenated protein alignments, prints script invocation arguments to STDOU at the beginning of the run, and prints a summary results of the different filtering steps before exiting. Read the [**Release v2.2.0**)](https://github.com/vinuesa/get_phylomarkers/releases/tag/2.2.0) notes for further details. Note that users of this release interested in run mode 2 (-R 2) for to compute a population tree, will need to install [snp-sites](https://github.com/sanger-pathogens/snp-sites), as explained in the current [INSTALL.md notes](https://github.com/vinuesa/get_phylomarkers/blob/master/INSTALL.md).
18
+
- <code>run_get_phylomarkers_pipeline.sh</code> now also calls the C binary [**WEIGHTED-ASTRAL**](https://github.com/chaoszhang/ASTER) to estimate a species tree using as input the filtered gene trees estimated by [iqtree2](http://www.iqtree.org/) or [FastTree](http://www.microbesonline.org/fasttree/) from the core-genome clusters computed by [get_homologues](https://github.com/eead-csic-compbio/get_homologues).
19
+
20
+
- The main script <code>run_get_phylomarkers_pipeline.sh</code> added complex protein mixture models for concatenated protein alignments, prints script invocation arguments to STDOU at the beginning of the run, and prints a summary results of the different filtering steps before exiting. Read the [**Release v2.2.0**)](https://github.com/vinuesa/get_phylomarkers/releases/tag/2.2.0) notes for further details.
21
+
22
+
- Users of this release interested in run mode 2 (-R 2) to compute a population tree, will need to install [snp-sites](https://github.com/sanger-pathogens/snp-sites), as explained in the current [INSTALL.md notes](https://github.com/vinuesa/get_phylomarkers/blob/master/INSTALL.md).
23
+
24
+
- Linux users that cloned the the [GET_PHYLOMARKERS GitHub repository](https://github.com/vinuesa/get_phylomarkers) on **2024-04-15**, or later, will not have to install [snp-sites](https://github.com/sanger-pathogens/snp-sites) manually, because a static binary is provided (bin/linux/snp-sites-static), which is called by <code>run_get_phylomarkers_pipeline.sh v2.8.1.0_2024-04-15</code>. Thanks to Alfredo Hernández @ccg_unam for compiling snp-sites-static.
25
+
26
+
-[**Release 2.2.0** (2024-04-14)](https://github.com/vinuesa/get_phylomarkers/releases/tag/2.2.0) was used to build the *latest***Docker image** ready to pull from [**Docker Hub**](https://hub.docker.com/r/vinuesa/get_phylomarkers). On Dockerhub, you will find detailed instructions on installing and configuring the Docker client on your machine, pulling the latest image, and running the containerized instance of the GET_PHYLOMARKERS pipeline.
19
27
20
-
[**Release 2.2.0** (2024-04-14)](https://github.com/vinuesa/get_phylomarkers/releases/tag/2.2.0) was used to build the *latest***Docker image** ready to pull from [**Docker Hub**](https://hub.docker.com/r/vinuesa/get_phylomarkers). On Dockerhub, you will find detailed instructions on installing and configuring the Docker client on your machine, pulling the latest image, and running the containerized instance of the GET_PHYLOMARKERS pipeline.
21
28
22
29
**GET_PHYLOMARKERS** can also estimate **ML and parsimony trees from the pan-genome matrix**, including unsupervised learning methods to determine the optimal number of clusters from the pan-genome and average genomic distance matrices. A detailed [**manual**](https://vinuesa.github.io/get_phylomarkers/#get_phylomarkers-manual) and step-by-step [**tutorials**](https://vinuesa.github.io/get_phylomarkers/#get_phylomarkers-tutorial) document the software and help the user to get up and running quickly. For convenience, [**html**](https://vinuesa.github.io/get_phylomarkers/) and [**markdown**](https://github.com/vinuesa/get_phylomarkers/blob/master/docs/GET_PHYLOMARKERS_manual.md) versions of the documentation material are available.
0 commit comments