Deep learning in predicting functional effects of noncoding variants in brain-specific disorders
Data preprocessing
(e.g. RNA-seq, CHIP-seq, ATAC-seq, etc.)Data
andLabel
extraction for genomic bins (of interest)Numpy conversion
of data and labels (for DL usage)- DL training/Validation/Testing (demonstrated in
Training 3
subdirectory)
Note: A complete pipeline (R-based) automating the steps 1-3 can be found in full_pipeline.R
.