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update RM
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walterxie committed Apr 12, 2018
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Expand Up @@ -6,7 +6,6 @@ Models describing evolution at the codon level allow
the estimation of measures of the selective forces
acting on proteins
([Kosiol et. al. 2000](https://academic.oup.com/mbe/article-abstract/24/7/1464/986344)).

The available implementation is only M0 currently,
also called as GY94, first published by
[Goldman & Yang 1994](https://academic.oup.com/mbe/article-abstract/11/5/725/1008711),
Expand All @@ -21,6 +20,10 @@ can be calculated as:

The above two figures are copied from [Yang et al. 2000](http://www.genetics.org/content/155/1/431.short).

The model implementation in Java was ported from [BEAST 1](https://github.com/beast-dev/beast-mcmc) project.
The code was modified (including bug-fixing) to fit in [BEAST 2](https://github.com/CompEvol/beast2)
and also tested comparing with the [codeml](http://abacus.gene.ucl.ac.uk/software/paml.html) results.

## Tutorial

The tutorial is available in [wiki](https://github.com/BEAST2-Dev/codonmodels/wiki).
Expand Down Expand Up @@ -59,7 +62,8 @@ The xml to use __M0__ looks like:
```

Note: the tree likelihood has to use the codon alignment not the nucleotide alignment.
```

```xml
<distribution id="treeLikelihood" spec="ThreadedTreeLikelihood">
<data name="data" idref="codon.alignment"/>
<tree name="tree" idref="tree"/>
Expand Down Expand Up @@ -98,9 +102,9 @@ describing codon frequencies is increased.

## Citation

Dong Xie. (2017, November 1). Codon substitution models v1.0.0. Zenodo.
Dong Xie & Remco Bouckaert, (2018, April 12), Codon substitution models v1.1.0, Zenodo,
http://doi.org/10.5281/zenodo.1039992

## Note

This package is depending on BEAST 2.5.x, which will release on Match 2018.
This package is depending on BEAST 2.5.x.

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