2.2.0

INS Data Release 2.2.0

This data release was used along with the INS Data Model 2.2.0 for the 3.2.0 release of the Index of NCI Studies on December 18, 2025.

To access raw INS data files (TSV format), download the ins_data_files_2.2.0.0.zip below.

Key Changes

• Added datasets and downloadable file mappings from the Cancer Target Discovery and Development (CTD²) Network from the Center for Cancer Genomics
  • CTD² datasets (ctd_datasets_curated.tsv) were curated for INS from descriptive study pages on the CTD² Data Portal, which may no longer be supported after 2025
  • CTD² dataset-file mappings (ctd2_filedata.tsv) were curated for each .zip file available from CTD² Data Downloads, which may no longer be supported after 2025
  • Note: CTD² file downloads supported by INS are stored separately, not in this INS-Data repository
• Updated dbGaP primary disease annotations to improve accuracy and consistency
• This update does not include a rerun of the full data gathering pipeline. All previous TSVs not mentioned above remain unchanged.

Data Counts

Node Type	Unique IDs
program	166
dataset	7889
project	2666
grant	13549
publication	56003
file	82

Relevant Versions

Version	Tag
Data Build	2.2.0.0
Program Curation (Qualtrics)	2025-05-09 (manual fix)
Data Gathering Date	gathered-2025-05-15
iCite Version	2025-04
dbGaP Download	2025-05-19 (updated curation 2025-12-05)
CEDCD Received	2025-04-24
Data Model	2.2.0

Data Sources

Type	Sources
Programs	Curation
Projects	NIH RePORTER
Grants	NIH RePORTER
Publications	NIH RePORTER, PubMed, iCite
dbGaP Datasets	dbGaP, E-utilities, Curation
GED Datasets	GEO, E-utilities
CEDCD Datasets	CEDCD, Curation
CTD² Datasets, Files	CTD², Curation

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Full Changelog: 2.1.1...2.2.0

2.1.1

INS Data Release 2.1.1

This data release was used along with the INS Data Model 2.1.0 for the 3.1.1 patch release of the Index of NCI Studies on July 22, 2025.

To access raw INS data files (TSV format), download the ins_data_files_2.1.1.0.zip below.

Key Changes

• Replace NCI DOC values for some datasets with "Non-NIH-Funded". These are datasets where an NCI GPA managed the study data submission to dbGaP, but funding attribution is not appropriate.
• This update is a minor patch release and did not include a rerun of the full data gathering pipeline.

Data Counts

Node Type	Unique IDs
program	166
dataset	7791
project	2666
grant	13549
publication	56003

Relevant Versions

Version	Tag
Data Build	2.1.1.0
Program Curation (Qualtrics)	2025-05-09 (manual fix)
Data Gathering Date	gathered-2025-05-15
iCite Version	2025-04
dbGaP Download	2025-05-19
CEDCD Received	2025-04-24
Data Model	2.1.0

Data Sources

Type	Sources
Programs	Curation
Projects	NIH RePORTER
Grants	NIH RePORTER
Publications	NIH RePORTER, PubMed, iCite
dbGaP Datasets	dbGaP, E-utilities, Curation
GED Datasets	GEO, E-utilities
CEDCD Datasets	CEDCD, Curation

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Full Changelog: 2.1.0...2.1.1

2.1.0

INS Data Release 2.1.0

This data release was used along with the INS Data Model 2.1.0 for the 3.1.0 release of the Index of NCI Studies on June 10, 2025.

To access raw INS data files (TSV format), download the ins_data_files_2.1.0.1.zip below.

Key Changes

• Programs with Intramural Projects added to workflow
  • 700+ intramural projects from Center for Cancer Research (CCR) and Division of Cancer Epidemiology & Genetics programs added
  • Projects associated with automated downstream research outputs (publications and GEO datasets)
• Gene Expression Omnibus (GEO) datasets added to workflow
  • GEO accessions associated with publications (PMIDs) are automatically pulled using NCBI E-utilities
  • GEO metadata is pulled from GEO matrix files available through NCBI ftp server
  • Datasets are associated with upstream projects and programs also associated with the same publications
• Cancer Epidemiology Descriptive Cohort Database cohorts added to workflow
  • Cohort information is received from the CEDCD team and processed for integration with INS
• Improved dbGaP dataset handling
  • dbGaP dataset module now allows for iterative loops of manual curation and automated cleaning for better workflow integration
  • All data outputs (including dbGaP datasets) are now handled with the data packaging module for standardized finalization
• Implemented initial unit testing coverage with pytest
• Minor fixes and improvements to program and packaging modules
• Updated all input source files and regenerated all outputs

Data Counts

Node Type	Unique IDs
program	166
dataset	7791
project	2666
grant	13549
publication	56003

Relevant Versions

Version	Tag
Data Build	2.1.0.1
Program Curation (Qualtrics)	2025-05-09 (manual fix)
Data Gathering Date	gathered-2025-05-15
iCite Version	2025-04
dbGaP Download	2025-05-19
CEDCD Received	2025-04-24
Data Model	2.1.0

Data Sources

Type	Sources
Programs	Curation
Projects	NIH RePORTER
Grants	NIH RePORTER
Publications	NIH RePORTER, PubMed, iCite
dbGaP Datasets	dbGaP, E-utilities, Curation
GED Datasets	GEO, E-utilities
CEDCD Datasets	CEDCD, Curation

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Full Changelog: 2.0.0...2.1.0

2.0.0

INS Data Release 2.0.0

This data release was used along with INS Data Model 2.0.0 for the 3.0.0 release of the Index of NCI Studies on November 26, 2024.

Key Changes

• Datasets: New independent datasets module to gather and integrate study metadata from various public NCBI dbGaP resources:
  • dbGaP Study Metadata API
  • dbGaP SSTR API
  • dbGaP Advanced Search UI
  • Datasets gathered with this module were reviewed curated before release
  • Additional details in the readme
• Improvements to the Data Validation Excel generation to include tests for filter selections
• Improvements to handling of errors and edge cases in the Programs, Grants, and Publications modules

Data Counts

Node Type	Unique IDs
program	163
dataset	871
project	1899
grant	6376
publication	35339

Relevant Versions

Version	Tag
Data Build	2.0.0.4
Program Curation (Qualtrics)	2024-09-18 (manual fix)
Data Gathering Date	gathered-2024-09-20
iCite Version	2024-08
dbGaP Download	2024-08-30
Datasets Curation	2024-10-29
Data Model	2.0.0

Data Sources

Type	Sources
program	Curation
dataset	dbGaP, PubMed, Curation
project	NIH RePORTER
grant	NIH RePORTER
publication	NIH RePORTER, PubMed, iCite

Full Changelog: v1.1.0...2.0.0

v1.1.0

Release v1.1.0

INS Data Gathering pipeline release v1.1.0 for the Index of NCI Studies (INS) https://studycatalog.cancer.gov/. First introduced in the May 9th, 2024 release of INS v2.1.0.

Key Changes

• New data gathered from 2024-04-24 programs input file
• Formatting updates (special character handling, CSV escape workarounds)
• Support for separate cancer_type and focus_area program properties
• Data validation file updates

Relevant Versions

Version	Tag
Qualtrics Version	2024-04-24
Data Gathering Date	gathered-2024-04-26
iCite Version	2024-03
Qualtrics Type	manual_fix
Data Model	v1.0.1

Data Counts

Node Type	Unique IDs
program	83
project	757
grant	3065
publication	22199

Data Sources

Type	Sources
program	ODS Curation
project	NIH RePORTER
grant	NIH RePORTER
publication	NIH RePORTER, PubMed, iCite

v1.0.0

Release v1.0.0

Initial release of the INS Data Gathering pipeline. This release represents the first data gathered by this pipeline that will be included in the Index of NCI Studies (INS) https://studycatalog.cancer.gov/
Previous versions of INS used data gathered using the INS-ETL (Obsolete) repo. All data gathered using the old method have been removed and are no longer included in INS v2.0+.

Relevant Versions

Version	Tag
Qualtrics Version	2024-03-12
Data Gathering Date	gathered-2024-03-13
iCite Version	2024-02
Qualtrics Type	raw
Data Model	https://github.com/CBIIT/ins-model/tree/fb6185addcd82c6f535ebfa5dff39f8cb64ce262

Data Counts

Node Type	Unique IDs
program	83
project	757
grant	3047
publication	21898

Date Sources

Type	Sources
program	ODS Curation
project	NIH RePORTER
grant	NIH RePORTER
publication	NIH RePORTER, PubMed, iCite