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ChimPipe version 0.8.8

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@brguez brguez released this 12 Jun 13:40
· 103 commits to master since this release

New features

  • Pipeline able to take a bam file as input. Now it has two running modes: FASTQ and BAM as input.
  • Modifications in the way to run the pipeline and in the output directory structure to make it more flexible, clear and avoid some problems.
  • Pipeline configuration displayed in a clearer way.
  • Decreased the false positive rate. Remap only those multi-mappings with more than 10 hits instead of all the multi-mappings. This was leading to some false positives arising from alignment artifacts.

Bug fixes

  • Fixed a bug when an output directory is specified. Wrote in the cwd instead of the desired directory.
  • Fixed a problem in the step to extract mappings to remap in the second mapping phase. Missed alignments with 5 edit distance.
  • Fixed problem with reads split-mapping without canonical splice sites. Program was producing wrong formatted chimeras file.