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ChimPipe version 0.9.1

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@brguez brguez released this 17 Jan 10:09
· 53 commits to master since this release

New features

  • Multimapped split-reads considered for chimera detection.
  • New ChimPE module. Search for consistent paired-end supporting the existence of each chimeric junction. Chimeric junctions do not supported by at least one consistent paired-end will be discarded in the filtering module as false positives.
  • New ChimFilter module. Improves ChimPipe precision by filtering chimeric junctions according to 8 different criteria (number of spanning reads, consistent pairs, novel splice-sites, gene homology..). Completely tunable.
  • New output file containing the filtered chimeric junctions and the reason why they were filtered out.
  • Additional pieces of information provided for each chimeric junction (number of consistent paired-end, supporting reads identifier ...).

Bug fixes

  • Fixed problem in ChimSplice. Coordinates went into over the chromosome limits and the script failed, added an upper and lower bound.