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DeepNeuropePred:a robust tool to predict cleavage sites in neuropeptide precursors

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DeepNeuropePred:a robust tool to predict cleavage sites in neuropeptide precursors

We propose a novel deep learning framework "DeepNeuropePred", using a combination of pre-trained language model and Convolutional Neural Networks for feature extraction and predicting the neuropeptide cleavage sites.

Requirements

To install requirements:

pip install -r requirements.txt

🏷 Here, SignalP5 should be installed into your system environment

Evaluation

To evaluate the model on the 31 test proteins, run:

python test.py --model-file ./pretrain_model/DeepNeuropePred.pth --input-fasta ./data/test.txt --ouput-json ./data/predict.json

Results

Our model achieves the following performance on :

Model details

The methodological explanation of DeepNeuropePred

Contact

If you have any questions, comments, or would like to report a bug, please file a Github issue or contact me at wanglei94@hust.edu.cn.

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DeepNeuropePred:a robust tool to predict cleavage sites in neuropeptide precursors

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