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Automatic. Performs sequence database construction, quality control, multiple sequence alignment, tree construction, gene/species tree reconciliation, and ancestral reconstruction with minimal user input.
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Species aware. Integrates with the Open Tree of Life database, improving selection of sequences and tree/ancestor inference.
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Human-oriented. Users prepare input as spreadsheets, not arcane text files. Outputs are spreadsheets, clean fasta files, pdf trees, and graphical summaries of ancestor quality.
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Flexible. Use as a command line program or do custom analyses and plotting with the API.
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Modern. Topiary is built around a collection of modern, actively-supported, phylogenetic software tools:
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Python framework for doing ancestral sequence reconstruction
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Python framework for doing ancestral sequence reconstruction
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