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MMedzin committed May 24, 2023
2 parents ad275b8 + 9b642e8 commit f4ed27e
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83 changes: 83 additions & 0 deletions Projekt02-RNA-protein-bind/pattern.py
Original file line number Diff line number Diff line change
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from __future__ import annotations

from typing import Optional

import numpy as np


class Pattern:
def __init__(
self,
sequence: str,
fSHAPE: list[float],
file: Optional[str] = None,
start: int = -1,
end: int = -1,
):
"""
Creates instance of Pattern class.
Args:
sequence: a string with nucleotide sequence, e.g. "TNT"
fSHAPE: a list of float values representing reactivity of each nucleotide in sequence
file: an optional name of the origin file of the pattern
start: starting position of a sequence in a file
end: ending position of a sequence in a file
"""
self.sequence = sequence
self.seq_len = len(sequence)
self.fSHAPE = fSHAPE
self.file = file
self.start = start
self.end = end
self.associated_pattern: Optional[str] = None
self.zned = 0.0
self.ssf = 0.0
self.aS = 0.0

def matches_sequence(self, other_sequence: str, wildcard: str = "N") -> bool:
"""Check if two sequences are matching; `wildcard` can be any character"""
if len(self.sequence) != len(other_sequence):
print(f"Skipping a comparison: length mismatch")
return False

for ch1, ch2 in zip(self.sequence, other_sequence):
if ch1 not in [ch2, wildcard] and ch2 != wildcard:
return False
return True

def znormalized_euclidean_distance(self, other_fshape: list[float]):
"""Calculates the z-normalized Euclidean distance between two fSHAPE vectors"""
norm = np.linalg.norm(np.array(self.fSHAPE) - np.array(other_fshape))
if norm == 0:
self.zned = 0.0
else:
self.zned = norm / np.sqrt(len(self.fSHAPE))
self.update_aS()

def similarity_score(self, other_sequence: str):
"""Calculates the similarity score between two sequences"""
score = 0
for i in range(self.seq_len):
if self.matches_sequence(self.sequence[i], other_sequence[i]):
score += 2
elif any(
self.sequence[i] in x and other_sequence[i] in x
for x in ["AG", "CU", "CT", "UT"]
):
score += 1
self.ssf = score / self.seq_len
self.update_aS()

def update_aS(self):
self.aS = 10 * self.zned - self.ssf

def associate(self, other_pattern: Pattern):
"""Links the pattern with another matching pattern and updates similarity metrics"""
self.associated_pattern = other_pattern
self.znormalized_euclidean_distance(other_pattern.fSHAPE)
self.similarity_score(other_pattern.sequence)

def to_dict(self) -> dict:
repr = vars(self)
del repr["associated_pattern"]
return repr
58 changes: 58 additions & 0 deletions Projekt02-RNA-protein-bind/result_2023_04_01_0006.csv
Original file line number Diff line number Diff line change
@@ -0,0 +1,58 @@
sequence,seq_len,fSHAPE,file,start,end,zned,ssf,aS
GGAGGCTTAGA,11,"[0.524186081516, 0.629239161933, 0.273694677128, 1.20639572154, 2.38550829298, -0.408858281376, -0.442635374314, 0.178759360951, 0.0881279886496, 0.540480126543, 0.792368818708]",hnrnpa2b1_NM_002266_KPNA2.txt,1663,1674,0.8839297875166088,0.5454545454545454,8.293843329711542
AAAAATGTGAA,11,"[0.0538804345925, 0.732785701086, 0.651246522981, -0.191360425023, -0.27208568329, -0.205735221877, -0.176873477609, -0.122006798946, -0.210776848552, 2.15036154304, 0.18164683481]",hnrnpa2b1_NM_002032_FTH1.txt,559,570,1.038233703808837,1.0,9.38233703808837
AAAAATGTGAA,11,"[3.005425931, 1.03721442685, 1.58294992188, 0.716687355313, 1.89427244528, 1.95404721477, 0.359312088144, 1.26794415145, -0.624840364009, -0.292356612629, 1.34106601606]",hnrnpa2b1_NM_003905_NAE1.txt,884,895,1.0834373717831465,1.0,9.834373717831465
TCAGGCCTAGA,11,"[0.15162960692, 0.0943699158053, 0.115929612063, 0.811062249119, 1.12319942532, -0.0782117564791, -0.195387130363, -0.950020338584, -0.0965564357745, -0.296203068383, 0.574410427168]",hnrnpa2b1_NM_015658_NOC2L.txt,2376,2387,1.1724002231337811,0.5454545454545454,11.178547685883268
ATAGGCCTAGT,11,"[0.353187625054, 0.310284895132, 0.0739138895554, 0.380200041029, 0.0278032473946, 0.0234862343836, 0.396991684515, 0.657241232003, -0.316904752564, 0.882123603342, 1.15098405262]",hnrnpa2b1_NM_007363_NONO.txt,2895,2906,1.2604804881627982,0.5454545454545454,12.059350336173438
AAAGGCTTAGT,11,"[-0.335354926402, -0.0218629964184, 0.19943398674, 0.70177521048, 0.140911725913, -0.416426870541, 0.0954329624169, 0.549193589562, 1.84862357364, 1.61296142904, 1.10854939158]",hnrnpa2b1_NM_032412_CYSTM1.txt,776,787,1.272393839837737,0.5454545454545454,12.178483852922826
AAAGGGGTAGA,11,"[-0.404094930436, -0.0307341544954, 0.23329252376, -0.0107676841311, 0.00845920053569, 0.14627708814, -0.465288448773, 1.2302501645, 0.781189439665, 0.255800491752, 0.116018911598]",hnrnpa2b1_NM_005659_UFD1L.txt,847,858,1.2728273636555412,0.5454545454545454,12.182819091100866
TCAGGATTAGA,11,"[0.951321795026, 0.916430370816, 0.558449190359, 0.684564114001, 0.354075328342, 0.132496812215, 1.34830329926, 1.39909248502, 2.16041908432, -0.462765919833, -1.56583706258]",hnrnpa2b1_NM_006585_CCT8.txt,273,284,1.3208428647335082,0.5454545454545454,12.662974101880538
AGAGGGGTAGC,11,"[0.731061497368, 2.09949407151, 0.496603895614, -0.400893984379, 0.0805599442742, 0.000911102895514, -0.634965868778, -0.270270858077, -0.142031757683, 1.24063507139, 0.672561292842]",hnrnpa2b1_NM_013349_NENF.txt,348,359,1.4360210909564528,0.5454545454545454,13.814756364109984
CAAGGAGTAGG,11,"[1.79416128563, 1.68942221617, 0.12945543842, 1.19336462596, 1.5932653253, 2.96638654009, 1.64679212032, 1.90112549188, 0.361564400718, 0.285351094204, -0.400978595546]",hnrnpa2b1_NM_000942_PPIB.txt,810,821,1.4513956319562935,0.5454545454545454,13.96850177410839
CCAGGACTAGT,11,"[-0.103550854309, -0.245493173683, 1.85740274521, 0.344257954256, -1.63839496025, -0.73788888817, -0.433963149661, 0.154554650559, 0.94000587926, 0.348867272441, 0.428519001189]",hnrnpa2b1_NM_001286086_C11orf98.txt,330,341,1.4684825308472975,0.5454545454545454,14.13937076301843
ATAGGGTTAGA,11,"[-0.378438015775, 0.509225221828, 0.173087961559, 0.262261316066, 0.212201134537, 0.289544182599, 0.449903044042, -0.276195606027, 0.49224239744, 0.64010409793, 2.903708667]",hnrnpa2b1_NM_002810_PSMD4.txt,1253,1264,1.5008863400960657,0.5454545454545454,14.46340885550611
TTAGGTCTAGT,11,"[1.27999741465, 1.20768920075, -0.184363702484, 0.616547020776, -0.895136325827, -0.372585979245, -0.232269279966, -0.330781100142, -0.773632891258, -0.743111717296, -0.198004003837]",hnrnpa2b1_NM_002381_MATN3.txt,1876,1887,1.528102095452592,0.5454545454545454,14.735566409071374
TCAGGACTAGA,11,"[-0.0949823674869, -0.0778935534634, -0.232836142335, 0.0694808809271, -0.532566647067, -0.989667560372, 0.178940344891, 1.01742097205, -0.523208082225, 2.17912058259, 0.8653962192]",hnrnpa2b1_NM_002687_PNN.txt,2068,2079,1.5604587284251312,0.5454545454545454,15.059132738796768
TCAGGTCTAGG,11,"[1.89328715485, -0.829603266128, -0.605785198058, 1.13867114959, -0.755659818399, 0.528668748023, -0.579025958196, 0.204258379918, 0.0, 0.0, 0.912896076084]",hnrnpa2b1_NM_053035_MRPS33.txt,61,72,1.5771566089797384,0.5454545454545454,15.22611154434284
GAAGGTTTAGA,11,"[1.34810658098, -0.0210026308253, -0.206455949918, 0.167691945549, -0.29712188466, 0.791710857375, 1.87227225124, -0.0240219075983, 0.202975053128, 1.39444758751, 0.772718543269]",hnrnpa2b1_NM_018948_ERRFI1.txt,1767,1778,1.586683448916547,0.5454545454545454,15.32137994371092
TGAGGAGTAGG,11,"[-0.195407547738, 0.310214706613, 0.0575497330751, 0.0523748312036, -0.182165841623, -0.180554476634, 2.66452182335, 2.50430607708, -0.262643976479, -0.249035726221, -0.291043187994]",hnrnpa2b1_NM_001344_DAD1.txt,442,453,1.6056729692846277,0.5454545454545454,15.51127514739173
TTAGGCATAGA,11,"[3.43757289124, 2.60213064319, -0.400576813868, 2.54777023525, -0.164451074887, -0.574132918301, -0.798808261316, -0.242216346451, -0.904738562532, 0.498384103889, 0.114265071537]",hnrnpa2b1_NM_005896_IDH1.txt,424,435,1.6385424087999163,0.5454545454545454,15.83996954254462
CAAGGACTAGG,11,"[-1.34078697453, -0.951533911608, 0.198192928618, 0.276203879941, -1.54036679773, 0.564954239644, -0.867606487319, 0.574860738039, 1.03710067855, 0.540243543619, -0.919582928688]",hnrnpa2b1_NM_015871_ZNF593.txt,539,550,1.6839982874654358,0.5454545454545454,16.29452832919981
GGAGGAGTAGA,11,"[-0.582272215459, -0.617660022136, 0.143687509013, -0.60951615164, -0.714767391408, -0.427662769296, 1.03139568764, -0.183198211701, -0.402619657262, 0.948546720467, 1.28484349582]",hnrnpa2b1_NM_000014_A2M.txt,3389,3400,1.7086331462864046,0.5454545454545454,16.5408769174095
GTAGGAATAGT,11,"[0.841125886877, 1.33549368305, 0.0576917496566, -0.472639831492, -1.23153940437, 0.026874271956, 2.1563641126, 0.209484039463, 0.36979327835, -0.736554660311, -0.278439335069]",hnrnpa2b1_NM_000983_RPL22.txt,1133,1144,1.7579372728397895,0.5454545454545454,17.03391818294335
CGAGGGATAGC,11,"[-0.0431861959873, -0.01788982712, 1.07689862621, 1.76843388619, 1.92612454354, 1.63822701214, 0.89804188128, 4.80270126288, 3.95241723078, 0.0942756420985, -0.834190837778]",hnrnpa2b1_NM_006327_TIMM23.txt,694,705,1.7617854779142428,0.5454545454545454,17.07240023368788
AAAGGGATAGT,11,"[1.13820493607, -0.490401040933, -0.378406530034, -0.26231816021, -0.29607032811, -1.01698204606, -0.155345050641, -0.0250439482243, -1.48690078634, 2.4428374408, 0.222603389183]",hnrnpa2b1_NM_014762_DHCR24.txt,1975,1986,1.7829833548156566,0.5454545454545454,17.284379002702018
AAAGGCTTAGG,11,"[-0.812335437017, 0.494057491531, -0.929585457892, -0.603319788849, -0.84122995093, -1.06778601242, 1.59332283309, 2.46531821583, 0.291459142675, 0.418761122127, -0.300263320689]",hnrnpa2b1_NM_019058_DDIT4.txt,1125,1136,1.8221138566507744,0.5454545454545454,17.675684021053193
GCAGGCATAGC,11,"[0.0183362237915, -0.907537568858, -0.457490464244, -0.947070327225, -0.773904691565, 1.65550643417, 1.00518270101, 1.2973717221, -0.944666153724, -0.398651766042, -0.114801855628]",hnrnpa2b1_NM_000126_ETFA.txt,291,302,1.899749866237866,0.5454545454545454,18.452044116924117
GGAGGTTTAGG,11,"[-0.680109588826, -1.08261862679, -0.507882506515, -0.436024305684, -0.322097224219, -0.295538473254, 3.41371512096, 1.2183773511, -0.127987632642, -0.349062631465, -0.24947866039]",hnrnpa2b1_NM_021227_OSTC.txt,359,370,1.9365790037762176,0.5454545454545454,18.820335492307628
GGAGGTGTAGC,11,"[0.133652254661, -1.57458844381, -0.286932747342, -0.346302943185, -0.845048652665, -1.24514941753, 2.77922882482, 1.90542245404, 0.379815714343, 1.16214609165, 0.428765447937]",hnrnpa2b1_NR_002196_H19.txt,425,436,1.9516775177490275,0.5454545454545454,18.971320632035727
TAAGGAGTAGC,11,"[-0.840830516693, -0.933658626803, -0.324577191007, -0.628865754345, -1.68307900155, -1.8841621758, 1.11340626933, 1.27581136285, -0.749238780316, 0.476809870845, -0.592931260585]",hnrnpa2b1_NM_001128431_SLC39A14.txt,4082,4093,1.9854457635450484,0.5454545454545454,19.309003089995937
GAAGGAATAGA,11,"[-0.755189049888, -1.71846101411, -0.824057723695, -0.68010367011, -1.28968050068, 1.16411482728, 0.732685087896, 0.135716973937, -0.138199164076, 0.183699320257, 0.223018635664]",hnrnpa2b1_NM_004060_CCNG1.txt,897,908,1.988532148356602,0.5454545454545454,19.339866938111477
ATAGGGATAGG,11,"[3.25821402248, 2.18509061577, -0.162406104132, -0.248048557277, -0.589216423996, 0.824281685379, 2.46510962116, -0.12177711058, -0.701038880486, 0.00104062117371, -0.143387436926]",hnrnpa2b1_NM_005891_ACAT2.txt,446,457,1.9926424690028757,0.5454545454545454,19.380970144574206
CCAGGTGTAGT,11,"[0.494744742076, -0.539150932479, -0.785923791899, -1.09381545715, -1.22110994006, 0.169222249243, -0.240653315767, -0.392729386214, 0.0183640920878, -0.34371835739, 2.09292060362]",hnrnpa2b1_NM_014255_CNPY2.txt,434,445,2.0194598595772684,0.5454545454545454,19.64914405031813
GGAGGTTTAGG,11,"[0.0174523145836, 0.0725164950611, -0.026519129085, 0.00124720611335, 0.19070670076, 0.976721343182, 4.57639133632, 2.91148100677, 2.04200158035, 0.0865921701874, -0.0138208407076]",hnrnpa2b1_NR_002196_H19.txt,525,536,2.030076988801787,0.5454545454545454,19.75531534256332
TTAGGTTTAGC,11,"[4.91422533177, 3.87191524077, 0.426248372636, 2.06924678245, -0.568086771425, 1.2416921813, 1.05697664499, 1.6857619468, 0.74456337405, 1.38373208436, 0.960628322517]",hnrnpa2b1_NM_002902_RCN2.txt,1595,1606,2.0720749838894736,0.5454545454545454,20.17529529344019
ACAGGAGTAGT,11,"[-0.873610601148, -1.91881862085, -0.989517264761, -0.471991629278, -0.39506674588, -0.536120597044, -0.61221161093, -0.727361065456, -0.542931591927, -0.276729400829, 2.48922893468]",hnrnpa2b1_NM_000434_NEU1.txt,597,608,2.0789914917300423,0.5454545454545454,20.244460371845875
CCAGGTTTAGG,11,"[-0.220118062861, -0.70660686764, -0.186297835874, -0.61085328376, -1.7091099736, 0.139414624707, 1.65558786066, 0.502944810161, -0.253555217621, -0.246433078349, -3.21873951545]",hnrnpa2b1_NM_016245_HSD17B11.txt,1163,1174,2.111212033643017,0.5454545454545454,20.566665790975623
CTAGGGCTAGT,11,"[-0.0723729010591, -0.285077387939, -0.691025391489, -0.242112089541, -0.558643869859, -1.58254034424, -1.18224975066, -0.340673568904, 0.237679945433, 2.33467097276, 3.74661310882]",hnrnpa2b1_NM_005318_H1F0.txt,2121,2132,2.113328306687044,0.5454545454545454,20.587828521415894
GGAGGCCTAGT,11,"[-1.05618836559, -1.07888362968, -0.847968338205, -0.556702512473, -1.56444773345, -0.48910477515, -0.316630630551, -0.135050644315, -1.32750318769, 1.13009073692, 2.39688435144]",hnrnpa2b1_NM_001288_CLIC1.txt,99,110,2.1322904950032,0.5454545454545454,20.77745040457745
TAAGGCATAGG,11,"[1.94363818952, -1.26543931111, -0.869073427599, -1.26321666964, -0.679707823931, 1.21781710276, 2.22439072954, 0.562591881642, 0.377386777021, -0.666508672025, -0.942225489185]",hnrnpa2b1_NM_002026_FN1.txt,6471,6482,2.161297195567423,0.5454545454545454,21.067517410219683
ATAGGTATAGG,11,"[2.10263495865, 0.832232604011, -0.134080831607, -0.225452906628, -2.70782010292, -2.00474125177, -0.64232249752, -0.335983880164, -0.33734185891, -0.280417894081, -1.60308541597]",hnrnpa2b1_NM_005907_MAN1A1.txt,2557,2568,2.1672591021226086,0.5454545454545454,21.12713647577154
CCAGGAATAGT,11,"[-0.418170972209, -0.233944411246, -0.0990421456803, 0.0, -0.841404370879, -5.01224641039, 1.29766711873, 2.02985656512, 1.36272742026, 0.27202229764, 0.940203591523]",hnrnpa2b1_NR_003697_SNHG15.txt,214,225,2.189322358888324,0.5454545454545454,21.34776904342869
AAAGGAGTAGA,11,"[1.30383114642, -0.346607592378, -0.769628317217, -0.928157303668, -1.78540715558, -1.89005296135, -1.29646266995, -0.543841945852, -0.905617339988, -0.879483330276, -0.547226561145]",hnrnpa2b1_NM_000239_LYZ.txt,1279,1290,2.1900321852531697,0.5454545454545454,21.35486730707715
CCAGGAGTAGA,11,"[-0.603209948103, -1.00373179478, -0.269232849507, -0.954516395357, -1.27153536109, -1.82731568446, -1.31040863383, -1.1042560437, -1.07199418845, -1.20762065382, 2.12953547657]",hnrnpa2b1_NM_002026_FN1.txt,3698,3709,2.241662671885538,0.5454545454545454,21.87117217340084
AAAGGAGTAGA,11,"[-0.479478004364, -0.0223545293572, -0.0878235188134, 0.430801310783, -1.18682774717, -3.44104581553, 0.952213238521, 1.11858287905, -0.298535394216, 5.27206746263, 1.15857309186]",hnrnpa2b1_NM_005794_DHRS2.txt,1573,1584,2.333645499470109,0.5454545454545454,22.791000449246543
AAAGGAATAGT,11,"[4.26833182262, 0.999711877373, 0.279408562046, -0.323606921602, -1.82379109106, -0.474096782101, 1.92874033326, -0.34282119178, -2.23900111483, -1.39111996911, -0.517857138202]",hnrnpa2b1_NM_005313_PDIA3.txt,370,381,2.4109870941546974,0.5454545454545454,23.564416396092422
ACAGGGGTAGC,11,"[-1.78286059755, -1.76334635403, -0.98187784788, -0.952330397637, -0.24849479357, -3.14733164388, 2.68135061644, 0.563462486059, -2.4635847922, -0.150294865854, 0.0964058497226]",hnrnpa2b1_NM_033161_SURF4.txt,1786,1797,2.4658362000087,0.5454545454545454,24.112907454632456
GCAGGCTTAGA,11,"[-2.6593385485, -1.93373695565, -0.687742179701, -0.97118410616, -1.60248506807, 0.932018838371, 1.84703564257, 3.58993789028, -1.10016876094, -0.481206566277, -1.32507730813]",hnrnpa2b1_NM_002615_SERPINF1.txt,100,111,2.484829759175729,0.5454545454545454,24.30284304630274
GAAGGTGTAGA,11,"[-1.80550895356, -1.17979827601, -0.867052733061, -1.36455991718, -2.84959202938, -0.119446016846, 1.14749405174, 3.37192970554, -0.325461520952, 0.466562004755, -1.30641753081]",hnrnpa2b1_NM_004546_NDUFB2.txt,380,391,2.488986516387792,0.5454545454545454,24.344410618423368
GGAGGAGTAGG,11,"[-0.822566632888, -2.26407497571, -1.08284400741, -0.718079237856, -1.91392298924, -3.23665574183, 4.30215159037, 0.20419221067, -0.485903137698, -0.434304957161, -0.559281513756]",hnrnpa2b1_NM_004152_OAZ1.txt,791,802,2.7261881507807,0.5454545454545454,26.71642696235245
ATAGGAATAGT,11,"[5.36638550992, 2.94182589831, -0.00736690248804, -0.322642076108, -1.91384827781, -0.231331955073, -1.04069315407, 0.0395116042144, -1.63113399025, -2.84208346984, -2.2262895713]",hnrnpa2b1_NM_033161_SURF4.txt,1533,1544,2.790946007443801,0.5454545454545454,27.36400552898347
AAAGGTTTAGG,11,"[-0.121543438069, -1.94620811296, -0.629677919784, -3.87124126686, -2.48962172384, -0.614689388418, 1.77806835042, 0.811244553067, -0.767376488502, -1.31308119631, -0.980374977822]",hnrnpa2b1_NM_000638_VTN.txt,1254,1265,2.8984387833874585,0.5454545454545454,28.43893328842004
TCAGGAATAGA,11,"[-1.07926834444, -0.409374388638, -0.704684410919, -0.656834633404, 0.369079385039, 7.8112226218, 2.86010375581, 2.54199725503, -0.410464261807, 3.64312488288, -0.32279323349]",hnrnpa2b1_NM_001008_RPS4Y1.txt,185,196,3.146200280085743,0.5454545454545454,30.916548255402883
GTAGGAATAGC,11,"[9.34585878843, 2.54721759517, -0.00971066789241, 0.220209663919, -0.553271186528, -0.758000154437, -0.56297414082, 0.0375114651724, 0.805926777315, 0.267036630773, 0.0510497491392]",hnrnpa2b1_NM_001412_EIF1AX.txt,2419,2430,3.1621724596698924,0.5454545454545454,31.07627005124438
CGAGGAATAGG,11,"[-1.43532662019, -1.97272141506, -1.03542969323, -1.39176022232, -0.821382726495, 7.11732764498, 3.4315999337, -0.867465947027, -1.20899305708, -0.740316042144, -2.31678423875]",hnrnpa2b1_NM_198589_BSG.txt,166,177,3.345349787624892,0.5454545454545454,32.90804333079437
CTAGGTCTAGG,11,"[8.23801034355, 4.22831080539, 1.75569653671, -0.527991329353, -3.36676884188, -1.37095243265, -0.863336544561, -0.0106287192149, 0.0106809432145, 0.00331911464753, -2.42162793365]",hnrnpa2b1_NM_007355_HSP90AB1.txt,2293,2304,3.43236014402337,0.5454545454545454,33.778146894779155
GAAGGGCTAGT,11,"[11.8922222128, 1.56472833543, 0.387497665797, 0.694680661157, -0.24168869866, 0.0494645072279, 0.453071959645, 0.511526062102, -2.03812128373, 0.696092372831, -0.474423348817]",hnrnpa2b1_NM_033161_SURF4.txt,1767,1778,3.8356653282604265,0.5454545454545454,37.81119873714972
GAAGGAGTAGG,11,"[0.920435443219, -0.856109230874, -1.49865143093, -0.918014697053, -3.18071225577, -4.62468810059, 2.57422175473, -6.57061606072, -2.3039807438, -1.53507934661, -4.6744608148]",hnrnpa2b1_NM_002106_H2AFZ.txt,102,113,4.021606965532591,0.5454545454545454,39.67061510987136
AAAGGTATAGG,11,"[1.7141847121, -0.137869395077, -0.158894081451, -0.0246020831129, -2.26725638286, 8.70508917208, 10.5501974371, 6.25682050881, -2.98190903173, -0.990172242884, -3.1677723677]",hnrnpa2b1_NM_016286_DCXR.txt,63,74,5.003182490360733,0.5454545454545454,49.48637035815278
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