GitHub - ModelDBRepository/62286: Excitation-contraction coupling in an integrative heart cell model (Greenstein et al 2006)

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Excitation-contraction coupling in an integrative heart cell model (Greenstein et al 2006)

modeldb.science/62286

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Name		Name	Last commit message	Last commit date
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Script_40state.m		Script_40state.m
fcn_40state.m		fcn_40state.m
readme.html		readme.html
screenshot1.png		screenshot1.png
screenshot2.png		screenshot2.png

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<html><pre>
This is the readme for the model associated with the paper:

Greenstein JL, Hinch R, Winslow RL (2006) Mechanisms of
excitation-contraction coupling in an integrative model of the cardiac
ventricular myocyte. Biophys J 90(1):77-91
doi: <a href="http://dx.doi.org/10.1529/biophysj.105.065169">10.1529/biophysj.105.065169</a>

This model was contributed by JL Greenstein.

To run: extract this archive and run the command "Script_40state" in
matlab.  After a short time this image should appear:

<img src="./screenshot1.png" alt="screenshot 1" width="550">

When the axes are zoomed in to the first 400 ms this is similar to the
solid curve in Fig6 A in the paper:

<img src="./screenshot2.png" alt="screenshot 2" width="550">

Note: This model was formerly available at this link:
http://www.ccbm.jhu.edu/doc/software/Coupled LCC-RyR40state.zip
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