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Switched the extracellular volume back to 10x the cell volume to be c…
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…onsistent with current simulations.
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blakeaw committed Feb 24, 2023
1 parent 3ff682c commit 36b2121
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1 change: 0 additions & 1 deletion CHANGELOG.md
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* `util.run_model` has an input parameter `nprocs` that is passed to the solver's `run` function as `num_processors` to allow for parallel execution of the inputs if multiple parameter sets or initial conditions are provided.
* Moved `parm.variants.classic` to `parm.variants.twostate.classic`.
* Moved the existing `parm.variants.precoupled` to `parm.variants.twostate.precoupled`.
* `parm.receptor_modules` updated the extracellular volume to be 1000x the cell volume like the BNGL examples.

### Added
* `util.load_pydream_chains` function that can load the sampled parameter vectors output from PyDREAM sampling chains.
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4 changes: 2 additions & 2 deletions parm/compartments.py
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Expand Up @@ -157,7 +157,7 @@ def default_cell():
# https://github.com/RuleWorld/BNGTutorial/blob/master/CBNGL/LRR_comp.bngl
# https://github.com/RuleWorld/BNGTutorial/blob/master/CBNGL/LR_comp.bngl
# We'll use 10 time the cytosolic volume
Parameter("Vextra", Vcyto.value * 1000)
Parameter("Vextra", Vcyto.value * 10)
# Volume of the ER lumen/cisternal space.
# It is often >10% of cell volume according to
# Alberts et al. https://www.ncbi.nlm.nih.gov/books/NBK26841/ .
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# https://github.com/RuleWorld/BNGTutorial/blob/master/CBNGL/LRR_comp.bngl
# https://github.com/RuleWorld/BNGTutorial/blob/master/CBNGL/LR_comp.bngl
# We'll use 10 time the cytosolic volume
Parameter("Vextra", Vcyto.value * 1000)
Parameter("Vextra", Vcyto.value * 10)
# Volume of the ER lumen/cisternal space.
# It is often >10% of cell volume according to
# Alberts et al. https://www.ncbi.nlm.nih.gov/books/NBK26841/ .
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