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Biological Data currently not incorporated into the main Wiki sections
Once new biological data has been received on new compounds, the data will be put here in the interim before it is incorporated into the relevant main Wiki section.
2019 July Dundee Potency and the File Mirror on Github
July 2019 Metabolic/Physchem Data from Monash
June 2018 Monash Data (don't think it's on wiki)
May 2018 Metabolic/Physchem Data from Monash
Feb 2017 Metabolic/Physchem Data from Monash
Below this line are biological evaluations that have been installed on the wiki, and are listed as such in the section on Sources of Data
2014 June GSK Single Shot Potencies plus July analysis of the actives and the File Mirror on Github
2014 hERG data (figure in terms of IC50 or pIC50) file mirror
2014 Syngene Potency Received (Nov) and Sent (Sept) file mirror
2015 Nov Syngene Potency and the File Mirror on Github
2016 Jun Syngene Potency (sent May 2016) File Mirror on Github
2016 Nov Dundee Potency and the File Mirror on Github
2017 Jul Dundee Potency and the File Mirror on Github
2017 Oct Dundee Potency and the File Mirror on Github
2017 Dec Dundee Potency and the File Mirror on Github
2018 Feb Dundee Potency and the File Mirror on Github
2018 Apr Dundee Potency and the File Mirror on Github
Aims, Concerns and Current Interest in Series 4
Modification of Core Triazolopyrazine
Modification of Pyrazine Substitution Pattern
Modification of the Triazole Substitution
Pyrazine Side Chain Modifications - Ethers
Pyrazine Side Chain Modifications - Amides
Pyrazine Side Chain Modifications - Reversed Amides
Pyrazine Side Chain Modifications - Others
Biological Data Currently not Incorporated into the Main Wiki Sections
Mechanism of Action: Possible PfATP4 Activity Deduced from Parasite Ion Regulation Assays
Synthesis of the Ether-Linked Series
Synthesis of the Amide-Linked Series
Synthesis of the Reverse Amide- Linked Series
Synthesis of Benzylic Functionalised Ether-Linked Series
Alternative Routes to the Triazolopyrazine Core
Triazolopyrazine telesubstitution
Chirality/Stereogenic Centres in This Series
Other Sources of Compounds Relevant to this Series
Desirable Compounds Not Yet Synthesised