This is the readme for the model from the paper: Markaki M, Orphanoudakis S, Poirazi P (2005) Modelling reduced excitability in aged CA1 neurons as a calcium-dependent process Neurocomputing 65-66:305-314
These model files were supplied by Dr Poirazi.
The model files were changed slightly after the paper however they reproduce the traces in Figure 3.
Auto-launch from ModelDB or download and extract the archive and then
Compile the mod files with "nrnivmodl mechanism" , then start with
nrngui mosinit.hoc
Compile the mod files with mknrndll. Move the nrnmech.dll up one level to the top level directory. Double click on mosinit.hoc in a windows explorer.
Once the simulation has started press the run button to generate figures similar to the traces in Figure 2 (increased Ca2+):
20120201: cadL.mod, cad.mod, cadN.mod updated to derivimplicit as per http://www.neuron.yale.edu/phpBB/viewtopic.php?f=28&t=592