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title: MEME tags: [maunal, tools] date: 7/27/2016 6:40:19 PM

GCModeller [version 1.34.0.2]

Module AssemblyName: file:///G:/GCModeller/manual/bin/MEME.exe Root namespace: MEME.CLI

All of the command that available in this program has been list below:

Function API Info
/BBH.Select.Regulators Select bbh result for the regulators in RegPrecise database from the regulon bbh data.
/Build.FamilyDb
/Copys
/Copys.DIR
/CORN
/EXPORT.MotifDraws
/Export.MotifSites Motif iteration step 1
/Export.Regprecise.Motifs
/Export.Similarity.Hits Motif iteration step 2
/Footprints 3 - Generates the regulation footprints.
/Hits.Context 2
/LDM.Compares
/LDM.MaxW
/LDM.Selects
/MAST.MotifMatches
/MAST.MotifMatchs.Family 1
/mast.Regulations
/MAST_LDM.Build
/MEME.Batch Batch meme task by using tmod toolbox.
/MEME.LDMs
/Motif.BuildRegulons
/Motif.Info Assign the phenotype information And genomic context Info for the motif sites. [SimpleSegment] -> [MotifLog]
/Motif.Info.Batch [SimpleSegment] -> [MotifLog]
/Motif.Similarity Export of the calculation result from the tomtom program.
/MotifHits.Regulation
/Parser.DEGs
/Parser.Locus
/Parser.Log2
/Parser.MAST
/Parser.Modules
/Parser.Operon
/Parser.Pathway
/Parser.RegPrecise.Operons
/Parser.Regulon
/Parser.Regulon.gb
/Parser.Regulon.Merged
/Regulator.Motifs
/Regulator.Motifs.Test
/regulon.export
/Regulon.Reconstruct
/Regulon.Reconstruct2
/Regulon.Reconstructs Doing the regulon reconstruction job in batch mode.
/Regulon.Test
/RfamSites
/seq.logo
/Similarity.Union Motif iteration step 3
/Site.MAST_Scan [MAST.Xml] -> [SimpleSegment]
/Site.MAST_Scan.Batch [MAST.Xml] -> [SimpleSegment]
/Site.RegexScan
/site.scan
/SiteHits.Footprints Generates the regulation information.
/SWTOM.Compares
/SWTOM.Compares.Batch
/SWTOM.LDM
/SWTOM.Query
/SWTOM.Query.Batch
/Tom.Query
/Tom.Query.Batch
/TomTOM
/TomTom.LDM
/TomTOM.Similarity
/TOMTOM.Similarity.Batch
/TomTom.Sites.Groups
/Trim.MastSite
--build.Regulations Genome wide step 2
--build.Regulations.From.Motifs
--CExpr.WGCNA
Download.Regprecise Download Regprecise database from Web API
--Dump.KEGG.Family
--family.statics
--Get.Intergenic
--GetFasta
--hits.diff
--Intersect.Max
--logo.Batch
--mapped-Back
mast.compile
mast.compile.bulk Genome wide step 1
--modules.regulates Exports the Venn diagram model for the module regulations.
Motif.Locates
MotifScan Scan for the motif site by using fragment similarity.
--pathway.regulates Associates of the pathway regulation information for the predicted virtual footprint information.
Regprecise.Compile The repository parameter is a directory path which is the regprecise database root directory in the GCModeller directory, if you didn't know how to set this value, please leave it blank.
regulators.bbh Compiles for the regulators in the bacterial genome mapped on the regprecise database using bbh method.
regulators.compile Regprecise regulators data source compiler.
--site.Match
--site.Matches
--site.Matches.text Using this function for processing the meme text output from the tmod toolbox.
--site.stat Statics of the PCC correlation distribution of the regulation
--TCS.Module.Regulations
--TCS.Regulations
VirtualFootprint.DIP Associate the dip information with the Sigma 70 virtual footprints.
wGet.Regprecise Download Regprecise database from REST API

Commands


Help for command '/BBH.Select.Regulators':

Prototype: MEME.CLI::Int32 SelectRegulatorsBBH(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  Select bbh result for the regulators in RegPrecise database from the regulon bbh data.
  Usage:        G:\GCModeller\manual\bin\MEME.exe /BBH.Select.Regulators /in <bbh.csv> /db <regprecise_downloads.DIR> [/out <out.csv>]
  Example:      MEME /BBH.Select.Regulators 
Help for command '/Build.FamilyDb':

Prototype: MEME.CLI::Int32 BuildFamilyDb(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Build.FamilyDb /prot <RegPrecise.prot.fasta> /pfam <pfam-string.csv> [/out <out.Xml>]
  Example:      MEME /Build.FamilyDb 
Help for command '/Copys':

Prototype: MEME.CLI::Int32 BatchCopy(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Copys /in <inDIR> [/out <outDIR> /file <meme.txt>]
  Example:      MEME /Copys 
Help for command '/Copys.DIR':

Prototype: MEME.CLI::Int32 BatchCopyDIR(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Copys.DIR /in <inDIR> /out <outDIR>
  Example:      MEME /Copys.DIR 
Help for command '/CORN':

Prototype: MEME.CLI::Int32 CORN(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /CORN /in <operons.csv> /mast <mastDIR> /PTT <genome.ptt> [/out <out.csv>]
  Example:      MEME /CORN 
Help for command '/EXPORT.MotifDraws':

Prototype: MEME.CLI::Int32 ExportMotifDraw(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /EXPORT.MotifDraws /in <virtualFootprints.csv> /MEME <meme.txt.DIR> /KEGG <KEGG_Modules/Pathways.DIR> [/pathway /out <outDIR>]
  Example:      MEME /EXPORT.MotifDraws 
Help for command '/Export.MotifSites':

Prototype: MEME.CLI::Int32 ExportTestMotifs(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  Motif iteration step 1
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Export.MotifSites /in <meme.txt> [/out <outDIR> /batch]
  Example:      MEME /Export.MotifSites 
Help for command '/Export.Regprecise.Motifs':

Prototype: MEME.CLI::Int32 ExportRegpreciseMotifs(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe 
  Example:      MEME /Export.Regprecise.Motifs 
Help for command '/Export.Similarity.Hits':

Prototype: MEME.CLI::Int32 LoadSimilarityHits(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  Motif iteration step 2
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Export.Similarity.Hits /in <inDIR> [/out <out.Csv>]
  Example:      MEME /Export.Similarity.Hits 
Help for command '/Footprints':

Prototype: MEME.CLI::Int32 ToFootprints(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  3 - Generates the regulation footprints.
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Footprints /footprints <footprints.xml> /coor <name/DIR> /DOOR <genome.opr> /maps <bbhMappings.Csv> [/out <out.csv> /cuts <0.65> /extract]
  Example:      MEME /Footprints 

Parameters information:

       [/extract]
    Description:  Extract the DOOR operon when the regulated gene is the first gene of the operon.

    Example:      /extract ""


Accepted Types

/extract
Help for command '/Hits.Context':

Prototype: MEME.CLI::Int32 HitContext(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  2
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Hits.Context /footprints <footprints.Xml> /PTT <genome.PTT> [/out <out.Xml> /RegPrecise <RegPrecise.Regulations.Xml>]
  Example:      MEME /Hits.Context 
Help for command '/LDM.Compares':

Prototype: MEME.CLI::Int32 CompareMotif(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /LDM.Compares /query <query.LDM.Xml> /sub <subject.LDM.Xml> [/out <outDIR>]
  Example:      MEME /LDM.Compares 
Help for command '/LDM.MaxW':

Prototype: MEME.CLI::Int32 LDMMaxLen(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /LDM.MaxW [/in <sourceDIR>]
  Example:      MEME /LDM.MaxW 
Help for command '/LDM.Selects':

Prototype: MEME.CLI::Int32 Selectes(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /LDM.Selects /trace <footprints.xml> /meme <memeDIR> [/out <outDIR> /named]
  Example:      MEME /LDM.Selects 
Help for command '/MAST.MotifMatches':

Prototype: MEME.CLI::Int32 MotifMatch2(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /MAST.MotifMatches /meme <meme.txt.DIR> /mast <MAST_OUT.DIR> [/out <out.csv>]
  Example:      MEME /MAST.MotifMatches 
Help for command '/MAST.MotifMatchs.Family':

Prototype: MEME.CLI::Int32 MotifMatch(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  1
  Usage:        G:\GCModeller\manual\bin\MEME.exe /MAST.MotifMatchs.Family /meme <meme.txt.DIR> /mast <MAST_OUT.DIR> [/out <out.Xml>]
  Example:      MEME /MAST.MotifMatchs.Family 
Help for command '/mast.Regulations':

Prototype: MEME.CLI::Int32 MastRegulations(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /mast.Regulations /in <mastSites.Csv> /correlation <sp_name/DIR> /DOOR <DOOR.opr> [/out <footprint.csv> /cut <0.65>]
  Example:      MEME /mast.Regulations 
Help for command '/MAST_LDM.Build':

Prototype: MEME.CLI::Int32 BuildPWMDb(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /MAST_LDM.Build /source <sourceDIR> [/out <exportDIR:=./> /evalue <1e-3>]
  Example:      MEME /MAST_LDM.Build 
Help for command '/MEME.Batch':

Prototype: MEME.CLI::Int32 MEMEBatch(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  Batch meme task by using tmod toolbox.
  Usage:        G:\GCModeller\manual\bin\MEME.exe /MEME.Batch /in <inDIR> [/out <outDIR> /evalue <1> /nmotifs <30> /mod <zoops> /maxw <100>]
  Example:      MEME /MEME.Batch 

Parameters information:

    /in
    Description:  A directory path which contains the fasta sequence for the meme motifs analysis.

    Example:      /in ""

   [/out]
    Description:  A directory path which outputs the meme.txt data to that directory.

    Example:      /out ""


Accepted Types

/in
/out
Help for command '/MEME.LDMs':

Prototype: MEME.CLI::Int32 MEME2LDM(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /MEME.LDMs /in <meme.txt> [/out <outDIR>]
  Example:      MEME /MEME.LDMs 
Help for command '/Motif.BuildRegulons':

Prototype: MEME.CLI::Int32 BuildRegulons(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Motif.BuildRegulons /meme <meme.txt.DIR> /model <FootprintTrace.xml> /DOOR <DOOR.opr> /maps <bbhmappings.csv> /corrs <name/DIR> [/cut <0.65> /out <outDIR>]
  Example:      MEME /Motif.BuildRegulons 
Help for command '/Motif.Info':

Prototype: MEME.CLI::Int32 MotifInfo(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  Assign the phenotype information And genomic context Info for the motif sites. [SimpleSegment] -> [MotifLog]
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Motif.Info /loci <loci.csv> [/motifs <motifs.DIR> /gff <genome.gff> /atg-dist 250 /out <out.csv>]
  Example:      MEME /Motif.Info 

Parameters information:

    /loci
    Description:  The motif site info data set, type Is simple segment.

    Example:      /loci ""

/motifs
    Description:  A directory which contains the motifsitelog data in the xml file format. Regulogs.Xml source directory

    Example:      /motifs ""


Accepted Types

/loci
/motifs
Help for command '/Motif.Info.Batch':

Prototype: MEME.CLI::Int32 MotifInfoBatch(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  [SimpleSegment] -> [MotifLog]
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Motif.Info.Batch /in <sites.csv.inDIR> /gffs <gff.DIR> [/motifs <regulogs.motiflogs.MEME.DIR> /num_threads -1 /atg-dist 350 /out <out.DIR>]
  Example:      MEME /Motif.Info.Batch 

Parameters information:

    /motifs
    Description:  Regulogs.Xml source directory

    Example:      /motifs ""

   [/num_threads]
    Description:  Default Is -1, means auto config of the threads number.

    Example:      /num_threads ""


Accepted Types

/motifs
/num_threads
Help for command '/Motif.Similarity':

Prototype: MEME.CLI::Int32 MEMETOM_MotifSimilarity(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  Export of the calculation result from the tomtom program.
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Motif.Similarity /in <tomtom.DIR> /motifs <MEME_OUT.DIR> [/out <out.csv> /bp.var]
  Example:      MEME /Motif.Similarity 
Help for command '/MotifHits.Regulation':

Prototype: MEME.CLI::Int32 HitsRegulation(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /MotifHits.Regulation /hits <motifHits.Csv> /source <meme.txt.DIR> /PTT <genome.PTT> /correlates <sp/DIR> /bbh <bbhh.csv> [/out <out.footprints.Csv>]
  Example:      MEME /MotifHits.Regulation 
Help for command '/Parser.DEGs':

Prototype: MEME.CLI::Int32 ParserDEGs(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Parser.DEGs /degs <deseq2.csv> /PTT <genomePTT.DIR> /door <genome.opr> /out <out.DIR> [/log-fold 2]
  Example:      MEME /Parser.DEGs 
Help for command '/Parser.Locus':

Prototype: MEME.CLI::Int32 ParserLocus(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Parser.Locus /locus <locus.txt> /PTT <genomePTT.DIR> /DOOR <genome.opr> [/out <out.DIR>]
  Example:      MEME /Parser.Locus 
Help for command '/Parser.Log2':

Prototype: MEME.CLI::Int32 ParserLog2(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Parser.Log2 /in <log2.csv> /PTT <genomePTT.DIR> /DOOR <genome.opr> [/factor 1 /out <outDIR>]
  Example:      MEME /Parser.Log2 
Help for command '/Parser.MAST':

Prototype: MEME.CLI::Int32 ParserMAST(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Parser.MAST /sites <mastsites.csv> /ptt <genome-context.pttDIR> /door <genome.opr> [/out <outDIR>]
  Example:      MEME /Parser.MAST 
Help for command '/Parser.Modules':

Prototype: MEME.CLI::Int32 ModuleParser(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Parser.Modules /KEGG.Modules <KEGG.modules.DIR> /PTT <genomePTT.DIR> /DOOR <genome.opr> [/locus <union/initx/locus, default:=union> /out <fasta.outDIR>]
  Example:      MEME /Parser.Modules 
Help for command '/Parser.Operon':

Prototype: MEME.CLI::Int32 ParserNextIterator(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Parser.Operon /in <footprint.csv> /PTT <PTTDIR> [/out <outDIR> /family /offset <50> /all]
  Example:      MEME /Parser.Operon 

Parameters information:

       [/family]
    Description:  Group the source by family? Or output the source in one fasta set

    Example:      /family ""


Accepted Types

/family
Help for command '/Parser.Pathway':

Prototype: MEME.CLI::Int32 PathwayParser(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Parser.Pathway /KEGG.Pathways <KEGG.pathways.DIR> /PTT <genomePTT.DIR> /DOOR <genome.opr> [/locus <union/initx/locus, default:=union> /out <fasta.outDIR>]
  Example:      MEME /Parser.Pathway 
Help for command '/Parser.RegPrecise.Operons':

Prototype: MEME.CLI::Int32 ParserRegPreciseOperon(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Parser.RegPrecise.Operons /operon <operons.Csv> /PTT <PTT_DIR> [/corn /DOOR <genome.opr> /id <null> /locus <union/initx/locus, default:=union> /out <outDIR>]
  Example:      MEME /Parser.RegPrecise.Operons 
Help for command '/Parser.Regulon':

Prototype: MEME.CLI::Int32 RegulonParser(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Parser.Regulon /inDIR <regulons.inDIR> /out <fasta.outDIR> /PTT <genomePTT.DIR> [/door <genome.opr>]
  Example:      MEME /Parser.Regulon 
Help for command '/Parser.Regulon.gb':

Prototype: MEME.CLI::Int32 RegulonParser2(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Parser.Regulon.gb /inDIR <regulons.inDIR> /out <fasta.outDIR> /gb <genbank.gbk> [/door <genome.opr>]
  Example:      MEME /Parser.Regulon.gb 
Help for command '/Parser.Regulon.Merged':

Prototype: MEME.CLI::Int32 RegulonParser3(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Parser.Regulon.Merged /in <merged.Csv> /out <fasta.outDIR> /PTT <genomePTT.DIR> [/DOOR <genome.opr>]
  Example:      MEME /Parser.Regulon.Merged 
Help for command '/Regulator.Motifs':

Prototype: MEME.CLI::Int32 RegulatorMotifs(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Regulator.Motifs /bbh <bbh.csv> /regprecise <genome.DIR> [/out <outDIR>]
  Example:      MEME /Regulator.Motifs 
Help for command '/Regulator.Motifs.Test':

Prototype: MEME.CLI::Int32 TestRegulatorMotifs(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Regulator.Motifs.Test /hits <familyHits.Csv> /motifs <motifHits.Csv> [/out <out.csv>]
  Example:      MEME /Regulator.Motifs.Test 
Help for command '/regulon.export':

Prototype: MEME.CLI::Int32 ExportRegulon(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /regulon.export /in <sw-tom_out.DIR> /ref <regulon.bbh.xml.DIR> [/out <out.csv>]
  Example:      MEME /regulon.export 
Help for command '/Regulon.Reconstruct':

Prototype: MEME.CLI::Int32 RegulonReconstruct(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Regulon.Reconstruct /bbh <bbh.csv> /genome <RegPrecise.genome.xml> /door <operon.door> [/out <outfile.csv>]
  Example:      MEME /Regulon.Reconstruct 
Help for command '/Regulon.Reconstruct2':

Prototype: MEME.CLI::Int32 RegulonReconstructs2(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Regulon.Reconstruct2 /bbh <bbh.csv> /genome <RegPrecise.genome.DIR> /door <operons.opr> [/out <outDIR>]
  Example:      MEME /Regulon.Reconstruct2 
Help for command '/Regulon.Reconstructs':

Prototype: MEME.CLI::Int32 RegulonReconstructs(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  Doing the regulon reconstruction job in batch mode.
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Regulon.Reconstructs /bbh <bbh_EXPORT_csv.DIR> /genome <RegPrecise.genome.DIR> [/door <operon.door> /out <outDIR>]
  Example:      MEME /Regulon.Reconstructs 

Parameters information:

    /bbh
    Description:  A directory which contains the bbh export csv data from the localblast tool.

    Example:      /bbh ""

/genome
    Description:  The directory which contains the RegPrecise bacterial genome downloads data from the RegPrecise web server.

    Example:      /genome ""

/door
    Description:  Door file which is the prediction data of the bacterial operon.

    Example:      /door ""


Accepted Types

/bbh
/genome
/door
Help for command '/Regulon.Test':

Prototype: MEME.CLI::Int32 RegulonTest(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Regulon.Test /in <meme.txt> /reg <genome.bbh.regulon.xml> /bbh <maps.bbh.Csv>
  Example:      MEME /Regulon.Test 
Help for command '/RfamSites':

Prototype: MEME.CLI::Int32 RfamSites(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /RfamSites /source <sourceDIR> [/out <out.fastaDIR>]
  Example:      MEME /RfamSites 
Help for command '/seq.logo':

Prototype: MEME.CLI::Int32 SequenceLogoTask(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /seq.logo /in <meme.txt> [/out <outDIR>]
  Example:      MEME /seq.logo 
Help for command '/Similarity.Union':

Prototype: MEME.CLI::Int32 UnionSimilarity(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  Motif iteration step 3
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Similarity.Union /in <preSource.fasta.DIR> /meme <meme.txt.DIR> /hits <similarity_hist.Csv> [/out <out.DIR>]
  Example:      MEME /Similarity.Union 
Help for command '/Site.MAST_Scan':

Prototype: MEME.CLI::Int32 SiteMASTScan(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  [MAST.Xml] -> [SimpleSegment]
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Site.MAST_Scan /mast <mast.xml/DIR> [/batch /out <out.csv>]
  Example:      MEME /Site.MAST_Scan 

Parameters information:

       [/batch]
    Description:  If this parameter presented in the CLI, then the parameter /mast will be used as a DIR.

    Example:      /batch ""


Accepted Types

/batch
Help for command '/Site.MAST_Scan.Batch':

Prototype: MEME.CLI::Int32 SiteMASTScanBatch(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  [MAST.Xml] -> [SimpleSegment]
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Site.MAST_Scan /mast <mast.xml.DIR> [/out <out.csv.DIR> /num_threads <-1>]
  Example:      MEME /Site.MAST_Scan.Batch 
Help for command '/Site.RegexScan':

Prototype: MEME.CLI::Int32 SiteRegexScan(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Site.RegexScan /meme <meme.txt> /nt <nt.fasta> [/batch /out <out.csv>]
  Example:      MEME /Site.RegexScan 
Help for command '/site.scan':

Prototype: MEME.CLI::Int32 SiteScan(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /site.scan /query <LDM.xml> /subject <subject.fasta> [/out <outDIR>]
  Example:      MEME /site.scan 
Help for command '/SiteHits.Footprints':

Prototype: MEME.CLI::Int32 SiteHitsToFootprints(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  Generates the regulation information.
  Usage:        G:\GCModeller\manual\bin\MEME.exe /SiteHits.Footprints /sites <MotifSiteHits.Csv> /bbh <bbh.Csv> /meme <meme.txt_DIR> /PTT <genome.PTT> /DOOR <DOOR.opr> [/queryHash /out <out.csv>]
  Example:      MEME /SiteHits.Footprints 
Help for command '/SWTOM.Compares':

Prototype: MEME.CLI::Int32 SWTomCompares(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /SWTOM.Compares /query <query.meme.txt> /subject <subject.meme.txt> [/out <outDIR> /no-HTML]
  Example:      MEME /SWTOM.Compares 
Help for command '/SWTOM.Compares.Batch':

Prototype: MEME.CLI::Int32 SWTomComparesBatch(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /SWTOM.Compares.Batch /query <query.meme.DIR> /subject <subject.meme.DIR> [/out <outDIR> /no-HTML]
  Example:      MEME /SWTOM.Compares.Batch 
Help for command '/SWTOM.LDM':

Prototype: MEME.CLI::Int32 SWTomLDM(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /SWTOM.LDM /query <ldm.xml> /subject <ldm.xml> [/out <outDIR> /method <pcc/ed/sw; default:=pcc>]
  Example:      MEME /SWTOM.LDM 
Help for command '/SWTOM.Query':

Prototype: MEME.CLI::Int32 SWTomQuery(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /SWTOM.Query /query <meme.txt> [/out <outDIR> /method <pcc> /bits.level 1.6 /minW 6 /no-HTML]
  Example:      MEME /SWTOM.Query 

Parameters information:

       [/no-HTML]
    Description:  If this parameter is true, then only the XML result will be export.

    Example:      /no-HTML ""


Accepted Types

/no-HTML
Help for command '/SWTOM.Query.Batch':

Prototype: MEME.CLI::Int32 SWTomQueryBatch(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /SWTOM.Query.Batch /query <meme.txt.DIR> [/out <outDIR> /SW-offset 0.6 /method <pcc> /bits.level 1.5 /minW 4 /SW-threshold 0.75 /tom-threshold 0.75 /no-HTML]
  Example:      MEME /SWTOM.Query.Batch 

Parameters information:

       [/no-HTML]
    Description:  If this parameter is true, then only the XML result will be export.

    Example:      /no-HTML ""


Accepted Types

/no-HTML
Help for command '/Tom.Query':

Prototype: MEME.CLI::Int32 TomQuery(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Tom.Query /query <ldm.xml/meme.txt> [/out <outDIR> /method <pcc/ed; default:=pcc> /cost <0.7> /threshold <0.65> /meme]
  Example:      MEME /Tom.Query 
Help for command '/Tom.Query.Batch':

Prototype: MEME.CLI::Int32 TomQueryBatch(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Tom.Query.Batch /query <inDIR> [/out <outDIR> /method <pcc/ed; default:=pcc> /cost 0.7 /threshold <0.65>]
  Example:      MEME /Tom.Query.Batch 
Help for command '/TomTOM':

Prototype: MEME.CLI::Int32 TomTOMMethod(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /TomTOM /query <meme.txt> /subject <LDM.xml> [/out <outDIR> /method <pcc/ed; default:=pcc> /cost <0.7> /threshold <0.3>]
  Example:      MEME /TomTOM 
Help for command '/TomTom.LDM':

Prototype: MEME.CLI::Int32 LDMTomTom(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /TomTom.LDM /query <ldm.xml> /subject <ldm.xml> [/out <outDIR> /method <pcc/ed/sw; default:=sw> /cost <0.7> /threshold <0.65>]
  Example:      MEME /TomTom.LDM 
Help for command '/TomTOM.Similarity':

Prototype: MEME.CLI::Int32 MEMEPlantSimilarity(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /TomTOM.Similarity /in <TOM_OUT.DIR> [/out <out.Csv>]
  Example:      MEME /TomTOM.Similarity 
Help for command '/TOMTOM.Similarity.Batch':

Prototype: MEME.CLI::Int32 MEMEPlantSimilarityBatch(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /TOMTOM.Similarity.Batch /in <inDIR> [/out <out.csv>]
  Example:      MEME /TOMTOM.Similarity.Batch 
Help for command '/TomTom.Sites.Groups':

Prototype: MEME.CLI::Int32 ExportTOMSites(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /TomTom.Sites.Groups /in <similarity.csv> /meme <meme.DIR> [/grep <regex> /out <out.DIR>]
  Example:      MEME /TomTom.Sites.Groups 
Help for command '/Trim.MastSite':

Prototype: MEME.CLI::Int32 Trim(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe /Trim.MastSite /in <mastSite.Csv> /locus <locus_tag> /correlations <DIR/name> [/out <out.csv> /cut <0.65>]
  Example:      MEME /Trim.MastSite 
Help for command '--build.Regulations':

Prototype: MEME.CLI::Int32 Build(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  Genome wide step 2
  Usage:        G:\GCModeller\manual\bin\MEME.exe --build.Regulations /bbh <regprecise.bbhMapped.csv> /mast <mastSites.csv> [/cutoff <0.6> /out <out.csv> /sp <spName> /DOOR <genome.opr> /DOOR.extract]
  Example:      MEME --build.Regulations 

Parameters information:

       [/DOOR.extract]
    Description:  Extract the operon structure genes after assign the operon information.

    Example:      /DOOR.extract ""


Accepted Types

/DOOR.extract
Help for command '--build.Regulations.From.Motifs':

Prototype: MEME.CLI::Int32 BuildFromMotifSites(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe --build.Regulations.From.Motifs /bbh <regprecise.bbhMapped.csv> /motifs <motifSites.csv> [/cutoff <0.6> /sp <spName> /out <out.csv>]
  Example:      MEME --build.Regulations.From.Motifs 
Help for command '--CExpr.WGCNA':

Prototype: MEME.CLI::Int32 WGCNAModsCExpr(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe --CExpr.WGCNA /mods <CytoscapeNodes.txt> /genome <genome.DIR|*.PTT;*.fna> /out <DIR.out>
  Example:      MEME --CExpr.WGCNA 
Help for command 'Download.Regprecise':

Prototype: MEME.CLI::Int32 DownloadRegprecise2(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  Download Regprecise database from Web API
  Usage:        G:\GCModeller\manual\bin\MEME.exe Download.Regprecise [/work ./ /save <saveXml>]
  Example:      MEME Download.Regprecise 
Help for command '--Dump.KEGG.Family':

Prototype: MEME.CLI::Int32 KEGGFamilyDump(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe --Dump.KEGG.Family /in <in.fasta> [/out <out.csv>]
  Example:      MEME --Dump.KEGG.Family 

Parameters information:

    /in
    Description:  The RegPrecise formated title fasta file.

    Example:      /in ""


Accepted Types

/in
Help for command '--family.statics':

Prototype: MEME.CLI::Int32 FamilyStatics(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe --family.statics /sites <motifSites.csv> /mods <directory.kegg_modules>
  Example:      MEME --family.statics 
Help for command '--Get.Intergenic':

Prototype: MEME.CLI::Int32 GetIntergenic(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe --Get.Intergenic /PTT <genome.ptt> /nt <genome.fasta> [/o <out.fasta> /len 100 /strict]
  Example:      MEME --Get.Intergenic 
Help for command '--GetFasta':

Prototype: MEME.CLI::Int32 GetFasta(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe --GetFasta /bbh <bbhh.csv> /id <subject_id> /regprecise <regprecise.fasta>
  Example:      MEME --GetFasta 
Help for command '--hits.diff':

Prototype: MEME.CLI::Int32 DiffHits(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe --hits.diff /query <bbhh.csv> /subject <bbhh.csv> [/reverse]
  Example:      MEME --hits.diff 
Help for command '--Intersect.Max':

Prototype: MEME.CLI::Int32 MaxIntersection(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe --Intersect.Max /query <bbhh.csv> /subject <bbhh.csv>
  Example:      MEME --Intersect.Max 
Help for command '--logo.Batch':

Prototype: MEME.CLI::Int32 LogoBatch(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe --logo.Batch -in <inDIR> [/out <outDIR>]
  Example:      MEME --logo.Batch 
Help for command '--mapped-Back':

Prototype: MEME.CLI::Int32 SiteMappedBack(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe --mapped-Back /meme <meme.text> /mast <mast.xml> /ptt <genome.ptt> [/out <out.csv> /offset <10> /atg-dist <250>]
  Example:      MEME --mapped-Back 
Help for command 'mast.compile':

Prototype: MEME.CLI::Int32 CompileMast(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe mast.compile /mast <mast.xml> /ptt <genome.ptt> [/no-meme /no-regInfo /p-value 1e-3 /mast-ldm <DIR default:=GCModeller/Regprecise/MEME/MAST_LDM> /atg-dist 250]
  Example:      MEME mast.compile 
Help for command 'mast.compile.bulk':

Prototype: MEME.CLI::Int32 CompileMastBuck(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  Genome wide step 1
  Usage:        G:\GCModeller\manual\bin\MEME.exe mast.compile.bulk /source <source_dir> [/ptt <genome.ptt> /atg-dist <500> /no-meme /no-regInfo /p-value 1e-3 /mast-ldm <DIR default:=GCModeller/Regprecise/MEME/MAST_LDM> /related.all]
  Example:      MEME mast.compile.bulk 

Parameters information:

       [/no-meme]
    Description:  Specific that the mast site construction will without and meme pwm MAST_LDM model.

    Example:      /no-meme ""


Accepted Types

/no-meme
Help for command '--modules.regulates':

Prototype: MEME.CLI::Int32 ModuleRegulates(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  Exports the Venn diagram model for the module regulations.
  Usage:        G:\GCModeller\manual\bin\MEME.exe --modules.regulates /in <virtualfootprints.csv> [/out <out.DIR> /mods <KEGG_modules.DIR>]
  Example:      MEME --modules.regulates 

Parameters information:

    /in
    Description:  The footprints data required of fill out the pathway Class, category and type information before you call this function.
                   If the fields is blank, then your should specify the /mods parameter.

    Example:      /in ""


Accepted Types

/in
Help for command 'Motif.Locates':

Prototype: MEME.CLI::Int32 MotifLocites(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe Motif.Locates -ptt <bacterial_genome.ptt> -meme <meme.txt> [/out <out.csv>]
  Example:      MEME Motif.Locates 
Help for command 'MotifScan':

Prototype: MEME.CLI::Int32 MotifScan(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  Scan for the motif site by using fragment similarity.
  Usage:        G:\GCModeller\manual\bin\MEME.exe MotifScan -nt <nt.fasta> /motif <motifLDM.xml/LDM_Name/FamilyName> [/delta <default:80> /delta2 <default:70> /offSet <default:5> /out <saved.csv>]
  Example:      MEME MotifScan 
Help for command '--pathway.regulates':

Prototype: MEME.CLI::Int32 PathwayRegulations(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  Associates of the pathway regulation information for the predicted virtual footprint information.
  Usage:        G:\GCModeller\manual\bin\MEME.exe --pathway.regulates -footprints <virtualfootprint.csv> /pathway <DIR.KEGG.Pathways> [/out <./PathwayRegulations/>]
  Example:      MEME --pathway.regulates 
Help for command 'Regprecise.Compile':

Prototype: MEME.CLI::Int32 CompileRegprecise(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  The repository parameter is a directory path which is the regprecise database root directory in the GCModeller directory, if you didn't know how to set this value, please leave it blank.
  Usage:        G:\GCModeller\manual\bin\MEME.exe Regprecise.Compile [<repository>]
  Example:      MEME Regprecise.Compile 
Help for command 'regulators.bbh':

Prototype: MEME.CLI::Int32 RegulatorsBBh(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  Compiles for the regulators in the bacterial genome mapped on the regprecise database using bbh method.
  Usage:        G:\GCModeller\manual\bin\MEME.exe regulators.bbh /bbh <bbhDIR/bbh.index.Csv> [/save <save.csv> /direct /regulons /maps <genome.gb>]
  Example:      MEME regulators.bbh 

Parameters information:

       [/regulons]
    Description:  The data source of the /bbh parameter is comes from the regulons bbh data.

    Example:      /regulons ""


Accepted Types

/regulons
Help for command 'regulators.compile':

Prototype: MEME.CLI::Int32 RegulatorsCompile()

  Information:  Regprecise regulators data source compiler.
  Usage:        G:\GCModeller\manual\bin\MEME.exe 
  Example:      MEME regulators.compile 
Help for command '--site.Match':

Prototype: MEME.CLI::Int32 SiteMatch(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe --site.Match /meme <meme.text> /mast <mast.xml> /out <out.csv> [/ptt <genome.ptt> /len <150,200,250,300,350,400,450,500>]
  Example:      MEME --site.Match 

Parameters information:

       [/len]
    Description:  If not specific this parameter, then the function will trying to parsing the length value from the meme text automatically.

    Example:      /len ""


Accepted Types

/len
Help for command '--site.Matches':

Prototype: MEME.CLI::Int32 SiteMatches(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe --site.Matches /meme <DIR.meme.text> /mast <DIR.mast.xml> /out <out.csv> [/ptt <genome.ptt>]
  Example:      MEME --site.Matches 
Help for command '--site.Matches.text':

Prototype: MEME.CLI::Int32 SiteMatchesText(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  Using this function for processing the meme text output from the tmod toolbox.
  Usage:        G:\GCModeller\manual\bin\MEME.exe --site.Matches.text /meme <DIR.meme.text> /mast <DIR.mast.xml> /out <out.csv> [/ptt <genome.ptt> /fasta <original.fasta.DIR>]
  Example:      MEME --site.Matches.text 
Help for command '--site.stat':

Prototype: MEME.CLI::Int32 SiteStat(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  Statics of the PCC correlation distribution of the regulation
  Usage:        G:\GCModeller\manual\bin\MEME.exe --site.stat /in <footprints.csv> [/out <out.csv>]
  Example:      MEME --site.stat 
Help for command '--TCS.Module.Regulations':

Prototype: MEME.CLI::Int32 TCSRegulateModule(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe --TCS.Module.Regulations /MiST2 <MiST2.xml> /footprint <footprints.csv> /Pathways <KEGG_Pathways.DIR>
  Example:      MEME --TCS.Module.Regulations 
Help for command '--TCS.Regulations':

Prototype: MEME.CLI::Int32 TCSRegulations(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  
  Usage:        G:\GCModeller\manual\bin\MEME.exe --TCS.Regulations /TCS <DIR.TCS.csv> /modules <DIR.mod.xml> /regulations <virtualfootprint.csv>
  Example:      MEME --TCS.Regulations 
Help for command 'VirtualFootprint.DIP':

Prototype: MEME.CLI::Int32 VirtualFootprintDIP(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  Associate the dip information with the Sigma 70 virtual footprints.
  Usage:        G:\GCModeller\manual\bin\MEME.exe VirtualFootprint.DIP vf.csv <csv> dip.csv <csv>
  Example:      MEME VirtualFootprint.DIP 
Help for command 'wGet.Regprecise':

Prototype: MEME.CLI::Int32 DownloadRegprecise(Microsoft.VisualBasic.CommandLine.CommandLine)

  Information:  Download Regprecise database from REST API
  Usage:        G:\GCModeller\manual\bin\MEME.exe wGet.Regprecise [/repository-export <dir.export, default: ./> /updates]
  Example:      MEME wGet.Regprecise 

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