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id: CARD017 | ||
specialty: cardiology | ||
topic: coronary artery disease | ||
difficulty: medium | ||
tags: [cardiovascular, outpatient, chronic, pharmacology, copilot01] | ||
created: 2025-01-10 | ||
lastUpdated: 2025-01-10 | ||
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# Stable Coronary Artery Disease Management | ||
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## Question | ||
A 62-year-old man with known coronary artery disease presents for medication adjustment. His history includes: | ||
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Medical History: | ||
- Prior NSTEMI 2 years ago with PCI to LAD | ||
- Type 2 diabetes (A1c 7.1%) | ||
- Hypertension | ||
- LDL 110 mg/dL on moderate-intensity statin | ||
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Current Status: | ||
- CCS Class II angina (symptoms with moderate exertion) | ||
- 2-3 episodes per week, responsive to sublingual nitroglycerin | ||
- Good medication compliance | ||
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Vital Signs: | ||
- BP: 142/88 mmHg | ||
- HR: 72/min | ||
- RR: 16/min | ||
- BMI: 27 kg/m² | ||
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Current Medications: | ||
- Aspirin 81mg daily | ||
- Atorvastatin 40mg daily | ||
- Metoprolol succinate 50mg daily | ||
- Lisinopril 20mg daily | ||
- Metformin 1000mg BID | ||
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Which medication change would be most appropriate? | ||
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## Options | ||
| Option | Description | | ||
|--------|-------------| | ||
| A) | Add ranolazine | | ||
| B) | Increase atorvastatin to 80mg | | ||
| C) | Switch to carvedilol | | ||
| D) | Add long-acting nitrate | | ||
| E) | Add second antiplatelet | | ||
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<details> | ||
<summary>View Answer</summary> | ||
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## Correct Answer | ||
B | ||
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## Explanation | ||
This case demonstrates key concepts in stable CAD management: | ||
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1. Why Increase Statin is Optimal: | ||
- LDL above secondary prevention goal (<70 mg/dL) | ||
- High-risk patient (diabetes + prior MI) | ||
- Room for dose escalation | ||
- Guidelines strongly recommend maximizing statin | ||
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2. Why Other Options Are Less Appropriate: | ||
- A) Ranolazine: Reserved for refractory symptoms | ||
- C) No clear advantage of carvedilol over metoprolol | ||
- D) Long-acting nitrates not first-line for occasional angina | ||
- E) DAPT typically not extended beyond 1 year post-PCI | ||
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3. Additional Considerations: | ||
- BP needs better control | ||
- Diabetes well-controlled | ||
- Appropriate use of evidence-based medications | ||
- Regular exercise should be encouraged | ||
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4. Secondary Prevention Goals: | ||
- LDL <70 mg/dL | ||
- BP <130/80 mmHg | ||
- A1c <7% | ||
- Regular exercise | ||
- Smoking cessation (if applicable) | ||
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## References | ||
- ACC/AHA Guidelines for Stable CAD 2022 | ||
- ESC Guidelines on Chronic Coronary Syndromes 2023 | ||
- JACC: Secondary Prevention of ASCVD 2022 | ||
</details> |