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Add: new stable coronary artery disease management question for outpa…
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Skippou committed Jan 10, 2025
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---
id: CARD017
specialty: cardiology
topic: coronary artery disease
difficulty: medium
tags: [cardiovascular, outpatient, chronic, pharmacology, copilot01]
created: 2025-01-10
lastUpdated: 2025-01-10
---

# Stable Coronary Artery Disease Management

## Question
A 62-year-old man with known coronary artery disease presents for medication adjustment. His history includes:

Medical History:
- Prior NSTEMI 2 years ago with PCI to LAD
- Type 2 diabetes (A1c 7.1%)
- Hypertension
- LDL 110 mg/dL on moderate-intensity statin

Current Status:
- CCS Class II angina (symptoms with moderate exertion)
- 2-3 episodes per week, responsive to sublingual nitroglycerin
- Good medication compliance

Vital Signs:
- BP: 142/88 mmHg
- HR: 72/min
- RR: 16/min
- BMI: 27 kg/m²

Current Medications:
- Aspirin 81mg daily
- Atorvastatin 40mg daily
- Metoprolol succinate 50mg daily
- Lisinopril 20mg daily
- Metformin 1000mg BID

Which medication change would be most appropriate?

## Options
| Option | Description |
|--------|-------------|
| A) | Add ranolazine |
| B) | Increase atorvastatin to 80mg |
| C) | Switch to carvedilol |
| D) | Add long-acting nitrate |
| E) | Add second antiplatelet |

<details>
<summary>View Answer</summary>

## Correct Answer
B

## Explanation
This case demonstrates key concepts in stable CAD management:

1. Why Increase Statin is Optimal:
- LDL above secondary prevention goal (<70 mg/dL)
- High-risk patient (diabetes + prior MI)
- Room for dose escalation
- Guidelines strongly recommend maximizing statin

2. Why Other Options Are Less Appropriate:
- A) Ranolazine: Reserved for refractory symptoms
- C) No clear advantage of carvedilol over metoprolol
- D) Long-acting nitrates not first-line for occasional angina
- E) DAPT typically not extended beyond 1 year post-PCI

3. Additional Considerations:
- BP needs better control
- Diabetes well-controlled
- Appropriate use of evidence-based medications
- Regular exercise should be encouraged

4. Secondary Prevention Goals:
- LDL <70 mg/dL
- BP <130/80 mmHg
- A1c <7%
- Regular exercise
- Smoking cessation (if applicable)

## References
- ACC/AHA Guidelines for Stable CAD 2022
- ESC Guidelines on Chronic Coronary Syndromes 2023
- JACC: Secondary Prevention of ASCVD 2022
</details>

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