An SGC Open Chemical Networks Project (number 18) devoted to the dengue virus (DENV) RdRp, focusing specifically on exploring the enamine library and virtual screening of this library against a site on the protein.
- For the science background, head to the wiki to check out the living paper that is being written there.
You contribute synthetic chemistry and in return the SGC offers biology. Together we can generate tool compounds to understand biology and validate drug targets to help cure disease. Everything is open, with all content governed by a CC-BY-4.0 licence.
If this sounds interesting, and you agree to the simple RULES, you can get started.
For answers to all the questions you have, go to the FAQs.
If you'd like to contact someone to talk about contributing, then write something in an Issue (see the tab above), which is a good way to communicate openly. (Issues describe what currently needs doing and act as a discussion forum - you need a Github account but it's super easy and not spammy. There's also an email address (chemistry@thesgc.org) you can use to ask questions. You can read more about all this in the "How To" Area
Please see the full list for more details
Professor Matthew Todd, University College London, Head of Chemistry Networks at the SGC - @mattodd
Professor Tim Willson, University of North Carolina Chapel Hill - @tmw20653
Dr Rebecka Isaksson, University College London, chemistry lead - @RebeckaIsaksson
Dr Peter Brown, University North Carolina Chapel Hill, project manager - @toluene44
Dr Rahman Saleem, University College London, project manager - @rahmanszsaleem
Dr Konstantin Popov, University North Carolina Chapel Hill, computational chemistry - @kipUNC
Dr Jessica Smith, Oregon Health & Science University, biological testing (antiviral assay)
Dr Anwar Hossain, University North Carolina Chapel Hill, compound managment - @ahsgc
Pharma Champion: Vacant.
The Sir James Murray Student Champion: vacant
Other Contributors To Date:
Potential Contributors:
You can see other contributors in the Issues (tab above).
The licence for the content of this project is, unless otherwise stated, and as for all OCN projects, CC-BY-4.0. This means you can do whatever you like with the project content, including making money, provided you cite the project.
This project is part of the SGC's Open Chemistry Networks initiative.
