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13 changes: 8 additions & 5 deletions README.md
Original file line number Diff line number Diff line change
@@ -1,6 +1,10 @@
# yeast-GEM: The consensus genome-scale metabolic model of _Saccharomyces cerevisiae_

[![DOI](https://zenodo.org/badge/52777598.svg)](https://zenodo.org/badge/latestdoi/52777598) [![GitHub version](https://badge.fury.io/gh/sysbiochalmers%2Fyeast-gem.svg)](https://badge.fury.io/gh/sysbiochalmers%2Fyeast-gem) [![Join the chat at https://gitter.im/SysBioChalmers/yeast-GEM](https://badges.gitter.im/SysBioChalmers/yeast-GEM.svg)](https://gitter.im/SysBioChalmers/yeast-GEM?utm_source=badge&utm_medium=badge&utm_campaign=pr-badge&utm_content=badge)[![Memote history](https://github.com/SysBioChalmers/yeast-GEM/workflows/Memote%20history/badge.svg)](https://sysbiochalmers.github.io/yeast-GEM/history_report.html)
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[![DOI](https://zenodo.org/badge/52777598.svg)](https://zenodo.org/badge/latestdoi/52777598)


# Description

Expand All @@ -9,7 +13,7 @@ This repository contains the current consensus genome-scale metabolic model of _
# Citation

* If you use yeast-GEM please cite the yeast9 paper:
> Zhang, C. et al. _Yeast9: a consensus yeast metabolic model enables quantitative analysis of cellular metabolism by incorporating big data._ bioRxiv (2023) doi:[10.1101/2023.12.03.569754](https://doi.org/10.1101/2023.12.03.569754)
> Zhang, C. et al. _Yeast9: a consensus genome-scale metabolic model for S. cerevisiae curated by the community._ Molecular Systems Biology (2024) doi:[10.1038/s44320-024-00060-7](https://doi.org/10.1038/s44320-024-00060-7)
* For pre-yeast9 versions:
> Lu, H. et al. _A consensus S. cerevisiae metabolic model Yeast8 and its ecosystem for comprehensively probing cellular metabolism._ Nature Communications 10, 3586 (2019). doi:[10.1038/s41467-019-11581-3](https://doi.org/10.1038/s41467-019-11581-3)
* Additionally, all yeast-GEM releases are archived in [Zenodo](https://zenodo.org/badge/latestdoi/52777598), for you to cite the specific version of yeast-GEM that you used in your study, to ensure reproducibility. You should always cite the original publication + the specific version, for instance:
Expand Down Expand Up @@ -99,10 +103,9 @@ Before opening Python, the following command should (once) be run in the yeast-G
io.write_yeast_model(model) # saving
```

### Online visualization/simulation
### Online visualization

* You can visualize selected pathways of yeast-GEM and perform online constraint-based simulations using [Caffeine](https://caffeine.dd-decaf.eu/interactive-map), by creating a simulation with the latest yeast-GEM version available, and choosing any _S. cerevisiae_ map (currently only `iMM904` maps are available). Learn more [about Caffeine](https://caffeine.dd-decaf.eu).
* Additionally, you can interactively navigate model components and visualize 3D representations of all compartments and subsystems of yeast-GEM at [Metabolic Atlas](https://metabolicatlas.org/explore?selected=Yeast-GEM). Learn more [about Metabolic Atlas](https://www.metabolicatlas.org/about).
You can interactively navigate model components and visualize 3D representations of all compartments and subsystems of yeast-GEM at [Metabolic Atlas](https://metabolicatlas.org/explore?selected=Yeast-GEM). Learn more [about Metabolic Atlas](https://www.metabolicatlas.org/about).

# Contributing

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