##Purpose
To understand the intricacies of clustering methods on RNAseq data.
##Method
Analyze the same data set with different clustering methods. Ideally remain inside the R enviroment. Please view/add/edit to wiki for more.
###Clustering
- kohonen (Self Organizing Maps) - R, need to pick the # clusters
kmeans()
-hclust()
- CUT TREE(consistency between high vs low level analysis, smaller clusters are part of larger ones.- HTScluster - High throughput sequences. server, CPU intensive
- WGCNA -
hclust()
wrapper and ease of use "dynamic tree cut"
###Ordinations
- PCA
- MDS
- PCOA
- NMDS
- CoCA