Deforminator_PIL is a matlab graphical user interface for deformable linear registration of MRI images, and was developed for use in lung MRI. The algorithm performs Projective image registration, using a GUI interface in matlab, using the outline of the lung as the constraints. The technique assumes all images were acquired close to a target volume, typically Functional Residual Capacity (FRC) and that no large deviations in lung volume are present in the dataset. The technique will produce unreliable results for variations in lung volume >10-12% above or below target volume.
The original algorithm and interface was developed by Tatsuya Arai in early 2014, and has undergone a few revisions since its first incarnation. Rui Carlos Sá added a "wrapper", shared it using github and added a few add-ons in March 2014; Amran Asadi significantly improved usability of the GUI and produced a compiled version that only requires the free Matlab runtime environment (not full Matlab).