Comet v2023.01.0
What's Changed
- Address issue where a peptide with a low xcorr identified in a very poor/sparse spectrum would be assigned a good E-value. This is due to the majority of matched xcorr scores being "0" so any poor scoring match looks like a good outlier. To address this issue, Comet now randomly assigns roughly half of these "0" value xcorr scores a score associated with a single peak match within the xcorr histogram used for the E-value calculation. Thanks to D. Shteynberg for reporting the issue.
- Add "scale_fragmentNL" parameter entry which scales (multiplies) the neutral loss mass value by the number of modified residues in the fragment. Feature requested by A. Keller.
- Add contributions of fragment neutral loss peaks in preliminary (Sp) score; previously they only applied to the cross-correlation score.
- Correct bug where the fragment neutral loss peak was not analyzed if the primary fragment peak was not matched.
- Fix minor typo in command line help. by @mriffle in #30
New Contributors
Full Changelog: v2022.01.2...v2023.01.0
Contributors
mriffle