Welcome to my computational neuroscience playground! I'm a Doctoral Researcher at Universitätsklinikum Freiburg specializing in multi-modal brain analysis, building bridges between high-dimensional omics, spatial transcriptomics, and morphological phenotyping to decode brain function and pathology.
- Spatial Proteomics: multiplexed immunofluorescence
- Spatial Statistics: SpatialDE, SPARK, neighborhood analysis, cell-cell interactions
- Cross-platform Integration: scRNA-seq + spatial + morphological data fusion
- Integration Methods: WGCNA, MOFA, Seurat v5 integration, Harmony
- High-content Analysis: CellProfiler, ImageJ/Fiji pipelines
- Morphological Phenotyping: Feature extraction, cluster enrichment, trajectory analysis
- Calcium Imaging: GCaMP analysis, signal processing, event detection
- Microglia Morphology Atlas Construction: Multi-modal mapping
- Neurodegeneration: Multi-omics biomarker discovery in Alzheimer's/Parkinson's
- Brain Tumors: Glioma microenvironment, spatial heterogeneity
- Neuroinflammation: Microglia/astrocyte activation state
Primary Languages: R, Python, Bash
Analysis Tools: Seurat, Scanpy, MicroFaceV2, CellProfiler, Squidpy, Giotto
Workflow: MagiCAL, MicroFcae, Docker/Singularity, HPC/SLURM
Visualization: ggplot2, ComplexHeatmaps, plotly, Shiny dashboards
📍 Location: Freiburg, Germany
🌍 Languages: English (Fluent), German (A1), Hindi (Native)
🎯 Open to: Collaborations, consulting, and challenging multi-omics projects
"Complex biological systems demand multi-modal approaches. I build computational frameworks where genomics meets morphology, spatial organization meets function, and data layers converge into biological insight."