apollo

Includes analysis of networks and searching networks in PPI data.

Four Types of network algorithms are being implemented in the current Netpredictor system which are described below.

HeatS : The algorithm based on the recommendation techniques developed by Zhou et al.

Network Based Inference(NBI) : This method is also based on the two phase resource transfer as the HeatS algorithm. In addition this method extends extends the recommendation model by similarity between small molecules and sequence similarity between targets.

Random walk with Restart(RWR) : This method based on the concept of widely known pagerank algorithm which computes random walk-based “distance” from a node to every other nodes in a network.

Netcombo : NetCombo algorithm fuses the results of NBI and RWR. Its takes the parameters for both the algorithms and averages the results.