Skip to content

📝 Detecting T-cell expansion and quantifying clone survival from deep profiling of immune repertoires

License

Notifications You must be signed in to change notification settings

antigenomics/vdjtrack

Folders and files

NameName
Last commit message
Last commit date

Latest commit

 

History

24 Commits
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Repository files navigation

VDJtrack pipeline

An approach to evaluation of clonotype sampling in immune repertoire profiling time courses.

Contents:

  • data/ the folder can be populated with data used in present study by running fetch_data.sh
  • code/ all code used in this study
  • example.Rmd and example/ a small example illustrating application of VDJtrack to monitor Yellow Fever Virus-specific clonotype induction at 2nd week post vaccination in a group of 6 volunteers

For comparing samples from different donor cohorts see the code/DLI_compare.Rmd template. Alternativey one can use example.Rmd with pooled samples by specifying CDR3s from samples of interest in the annotations.txt.

About

📝 Detecting T-cell expansion and quantifying clone survival from deep profiling of immune repertoires

Resources

License

Stars

Watchers

Forks

Releases

No releases published

Packages

No packages published