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bluenote-1577 authored Dec 23, 2023
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sylph uses a k-mer containment method, similar to sourmash or Mash. sylph's novelty lies in **using a statistical technique to correct ANI for low coverage genomes** within the sample, allowing accurate ANI queries for even low abundance genomes.

## Changelog

### Version v0.5.0 - Dec 23, 2023. Major breaking update.

#### IMPORTANT

* Big sensitivity boost for real illumina profiling in v0.5 versus v0.4.
* Breaking change: *.sylsp files are now a new format. Old sketches will no longer work.

See the [CHANGELOG](https://github.com/bluenote-1577/sylph/blob/main/CHANGELOG.md) for complete details.


## Install (current version v0.5.0)

#### Option 1: conda install
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