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Scripts developed for Orange and San Luis Obispo County Public Health Laboratories

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APHL-Covid-Genomics

Scripts developed for Orange and San Luis Obispo County Public Health Laboratories

To Start: GISAID_Uploads/Start.sh

  • Create a new RUN directory with naming convention "SLO_2021-10-05"
    • Data source (PHL) _ yyyy-mm-dd
  • Enter new RUN directory
  • Add metadata to RUN directory
  • Create a "BaselineSamples.csv" file with Sample ID and baseline surveillance
  • Create new directory "Fasta_Pieces"
  • Fill Fasta_Pieces with individual assemblies
  • Run GISAID_Uploads/Start.sh according to GISAID_Uploads/README.md

What This Does:

  • Format Assemblies for GISAID
    • Take individual assemblies, change headers to "hCoV-19/USA/CA-{name here}-##/2021"
    • Concatenate files into All_good.fasta
  • Format Assemblies for Aspen
    • Just concatenate files
  • Format Assemblies for GenBank
    • Takes input of Baseline surveillance status
    • Adds keyword to fasta header of surveillance samples
  • Perform Assembly_QC on Samples
    • Checks coverage
    • Checks # of consecutive unambiguous nucleotides (>10k)

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Scripts developed for Orange and San Luis Obispo County Public Health Laboratories

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