Coverage Calculator

A Streamlit-based calculator for planning sequencing experiments. Easily estimate samples per flowcell, coverage depth, or region size for any platform and protocol.

Features

• Genome-wide or targeted panel calculations
• Preset protocols (WGS, exome, panels) and sequencing platforms (MiSeq, MinION, etc.)
• Handles sample number, depth, genome/target size, duplication, and more
• Advanced options for bias, fragment overlap, library complexity, and read filtering
• No spreadsheet needed—results and warnings update instantly

Customizing

• Edit protocols/panels: coverage_calculator/config/presets.yaml
• Edit platforms: coverage_calculator/config/platforms.yaml