Notes

This repository is the one-to-one translation of Julia's package https://github.com/insysbio/LikelihoodProfiler.jl of version 0.3.0.

Currently the Python's version is not maintained. Use https://github.com/insysbio/LikelihoodProfiler.py/issues if any help wanted.

Intro

LikelihoodProfiler is a package for identifiability analysis and confidence intervals evaluation which was originally

written in Julia language. See https://github.com/insysbio/LikelihoodProfiler.jl

Installation

If your OS is Windows, you have to install NLopt wheel. Go to

https://www.lfd.uci.edu/~gohlke/pythonlibs/#nlopt

Download the wheel which suits you and install it with:

pip install NLopt-***.whl

Then clone LikelihoodProfiler from

https://github.com/insysbio/LikelihoodProfiler.py.git

Install LikelihoodProfiler requirements with:

pip install -r requirements.txt

Quick start

Plot simple profile:

from likelihoodprofiler import get_interval
f_3p_1im_dep = lambda x: 5.0 + (x[0]-3.0)**2 + (x[0]-x[1]-1.0)**2 + 0*x[2]**2
res0 = get_interval(
    [3., 2., 2.1],
    0,
    lambda x: f_3p_1im_dep(x),
    "LIN_EXTRAPOL",
    loss_crit = 9)
res0.plot()