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Merge pull request #178 from keaven/tests-for-gsSurvCalendar
Tests for gsSurvCalendar
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test_that("gsSurvCalendar basic functionality works", { | ||
# Test default parameters | ||
x <- gsSurvCalendar() | ||
expect_s3_class(x, c("gsSurv", "gsDesign")) | ||
expect_equal(x$k, 3) # Default number of analyses | ||
expect_equal(x$test.type, 4) # Default test type | ||
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||
# Test calendar time input validation | ||
expect_error( | ||
gsSurvCalendar(calendarTime = c(24, 12, 36)), | ||
"calendarTime must be an increasing vector" | ||
) | ||
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||
# Test spending type options | ||
x_info <- gsSurvCalendar(spending = "information") | ||
x_cal <- gsSurvCalendar(spending = "calendar") | ||
expect_false(identical(x_info$n.I, x_cal$n.I)) | ||
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# Test minimum follow-up validation | ||
expect_error( | ||
gsSurvCalendar(calendarTime = c(12, 24), minfup = 25), | ||
"Minimum follow-up greater than study duration." | ||
) | ||
}) | ||
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||
test_that("gsSurvCalendar matches gsSurv under specific conditions", { | ||
# Create comparable designs | ||
cal_design <- gsSurvCalendar( | ||
test.type = 4, | ||
calendarTime = c(12, 24, 36), | ||
spending = "information", | ||
minfup = 6 | ||
) | ||
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||
# Get event counts for timing | ||
nevents <- sapply(cal_design$T, function(x) { | ||
xx <- nEventsIA(tIA = x, x = cal_design, simple = FALSE) | ||
sum(xx$eDC) + sum(xx$eDE) | ||
}) | ||
timing <- nevents / max(nevents) | ||
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# Create matching gsSurv design | ||
surv_design <- gsSurv( | ||
k = 3, | ||
test.type = 4, | ||
timing = timing, | ||
T = max(cal_design$T), | ||
minfup = 6 | ||
) | ||
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||
# Compare key outputs | ||
expect_equal(cal_design$n.I, surv_design$n.I, tolerance = 1e-4) | ||
expect_equal(cal_design$lower$bound, surv_design$lower$bound, tolerance = 1e-4) | ||
expect_equal(cal_design$upper$bound, surv_design$upper$bound, tolerance = 1e-4) | ||
}) | ||
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||
test_that("gsSurvCalendar handles different spending functions", { | ||
# Test with O'Brien-Fleming spending | ||
x_of <- gsSurvCalendar( | ||
sfu = gsDesign::sfLDOF, | ||
sfl = gsDesign::sfLDOF, | ||
calendarTime = c(12, 24, 36), | ||
spending = "information" | ||
) | ||
expect_s3_class(x_of, c("gsSurv", "gsDesign")) | ||
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||
# Test with Pocock spending | ||
x_pocock <- gsSurvCalendar( | ||
sfu = gsDesign::sfLDPocock, | ||
sfl = gsDesign::sfLDPocock, | ||
calendarTime = c(12, 24, 36), | ||
spending = "information" | ||
) | ||
# Do Pocock spending with calendar time | ||
x_pocock_cal <- gsSurvCalendar( | ||
sfu = gsDesign::sfLDPocock, | ||
sfl = gsDesign::sfLDPocock, | ||
calendarTime = c(12, 24, 36), | ||
spending = "calendar" | ||
) | ||
expect_s3_class(x_pocock_cal, c("gsSurv", "gsDesign")) | ||
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# Verify different spending functions produce different bounds | ||
expect_false(identical(x_of$upper$bound, x_pocock$upper$bound)) | ||
expect_false(identical(x_pocock$upper$bound, x_pocock_cal$upper$bound)) | ||
# Verify cumulative spending matches spending function for information spending | ||
expect_equal( | ||
cumsum(x_pocock$upper$spend), | ||
gsDesign::sfLDPocock( | ||
alpha = x_pocock$alpha, | ||
t = x_pocock$upper$sTime | ||
)$spend, | ||
tolerance = 1e-4 | ||
) | ||
# Verify cumulative spending matches spending function for calendar time | ||
expect_equal( | ||
cumsum(x_pocock_cal$upper$spend), | ||
gsDesign::sfLDPocock( | ||
alpha = x_pocock_cal$alpha, | ||
t = x_pocock_cal$upper$sTime | ||
)$spend, | ||
tolerance = 1e-4 | ||
) | ||
# Verify spending time is proportion of full T | ||
expect_equal(x_pocock_cal$upper$sTime, x_pocock_cal$T / max(x_pocock_cal$T)) | ||
}) | ||
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test_that("gsSurvCalendar output structure is correct", { | ||
x <- gsSurvCalendar() | ||
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# Check essential components | ||
expected_names <- c( | ||
"k", "test.type", "alpha", "beta", "astar", | ||
"delta", "n.fix", "timing", "tol", "r", | ||
"n.I", "maxn.IPlan", "nFixSurv", "nSurv", "endpoint", | ||
"delta1", "delta0", "overrun", "usTime", "lsTime", | ||
"upper", "lower", "theta", "falseposnb", "en", | ||
"hr", "hr0", "R", "minfup", "gamma", | ||
"eDC", "eDE", "eNC", "eNE", "ratio", | ||
"lambdaC", "etaC", "etaE", "variable", "T" | ||
) | ||
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expect_true(all(expected_names %in% names(x))) | ||
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# Check dimensions of key components | ||
expect_equal(length(x$n.I), x$k) | ||
expect_equal(length(x$upper$bound), x$k) | ||
expect_equal(length(x$lower$bound), x$k) | ||
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# Check class attributes | ||
expect_true(inherits(x$upper, "spendfn")) | ||
expect_true(inherits(x$lower, "spendfn")) | ||
}) |