Accurate Detection of Spiking Motifs in Neurobiological Data by Learning Heterogeneous Delays of a Spiking Neural Network

• abstract: Recently, there has been an increased interest in exploring the hypothesis that neural activity conveys information through precise spiking motifs. To investigate this phenomenon, several algorithms have been proposed to detect such motifs in Single Unit Activity recorded from populations of neurons. Based on the inversion of a generative model of raster plot synthesis, we present a novel detection model. This model derives an optimal detection procedure in the form of logistic regression combined with temporal convolution. Its differentiability allows for a supervised learning approach using gradient descent on the binary cross-entropy loss. To assess the model's ability to detect spiking motifs in synthetic data, numerical evaluations are performed. This analysis emphasizes the benefits of utilizing spiking motifs instead of traditional firing rate-based population codes. Our learning method is able to successfully recover synthetically generated spiking motifs, indicating its potential for further applications. In the future, we aim to extend this method to real neurobiological data, where the ground truth is unknown, to explore and detect spiking motifs in a more natural and biologically relevant context.

• presented at 'FENS Forum 2024' - # PS01-26AM-128 / ABSTRACT NUMBER: 4728

• check out https://laurentperrinet.github.io/publication/perrinet-24-fens/

• get the poster https://laurentperrinet.github.io/publication/perrinet-24-fens/perrinet-24-fens.pdf

Poster generated using Gemini

Gemini is a modern LaTeX beamerposter theme.

If you're looking for a beamer presentation theme, take a look at Auriga.

Dependencies

• A TeX installation that includes LuaTeX
  • You also need latexmk if you want to use the provided Makefile
• LaTeX package dependencies including beamerposter (these usually come with your TeX installation, but if not, you can get them from CTAN)
• Raleway and Lato, which are both available under Open Font License

Usage

1. Copy the files in this repository (or clone the repository)

2. In poster.tex, set up your paper size, column layout, and scale the content as necessary

3. Make a copy of beamercolorthemegemini.sty, update the \usecolortheme line in poster.tex, and theme the poster to your liking (optional, but highly recommended)

4. Run make to build your poster

FAQ

See the FAQ in the Wiki for answers to frequently asked questions such as how to add an institution logo to the poster.

Themes

Gemini currently includes three color themes:

• gemini (default)
• mit
• labsix

The alternative themes are intended to be inspiration for you to make your own color theme. You're highly recommended to make your own color theme (it's really easy!) or use the default Gemini theme.

MIT theme

LabSix theme

Design goals

• Minimal: clean and easy to read, so that the emphasis is on the content
• Batteries included: works and looks good out of the box
• Easy theming: easy to create and use a new color theme

Contributing

Contributions to Gemini such as bug reports, new themes, and new poster components are greatly appreciated! Given the subjective nature of design, you're encouraged to open an issue or pull request early to get feedback before investing a lot of time in implementing a new feature.

License

Copyright (c) Anish Athalye. Released under the MIT License. See LICENSE.md for details.