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R package for Generalized Higher Criticism

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GHC

R Package to compute p-values for the Generalized Higher Criticism. P-values are computed analytically (by default) or through simulation of the null distribution (if specified) for the Generalized Higher Criticism test for SNP-sets in genome-wide association studies.

Reference

Barnett, I., Mukherjee, R., & Lin, X. (2017). The generalized higher criticism for testing SNP-set effects in genetic association studies. Journal of the American Statistical Association, 112(517), 64-76. doi:10.1080/01621459.2016.1192039.

License

The software is licensed under GPL-2.

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R package for Generalized Higher Criticism

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