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MEGPY - Combining MEGAN and PYthon for metagenomic analysis

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Collection of scripts for metagenomic downstream analysis of bioreactor data using the tool MEGAN and the programming language Python.

Installation

NOTE: REQUIREMENTS NOT ADDED YET PLEASE DOWNLOAD SCRIPTS MANUALLY FOR NOW TO USE THEM - WILL UPDATE THIS ONCE PROJECT IS FINISHED

1. Clone this repository
2. Navigate to repository
3. pip install .

Taxonomic analysis

taxonomy_plot.py

reads in multiple .daa files containing metagenomic reads mapped to NR database, extracts taxonomic information from them with MEGAN and then uses python's matplotlib to visualise the data

Functional analysis

gc_assembly.py

takes a .daa file as input as well as a SEED ID and computes a list with organisms in the .daa file that have the gene described by the ID. It uses gene centric assembly included with MEGAN as well as NCBI online Blast

strain_table.py

Takes BLAST results from gc_assembly_map and processes them. The output is a table with all enzymes that were targeted by the gc-assembly and the bacterial strains they are associated with in the .daa file

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Metagenome analysis - using MEGAN in python

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