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Nicolás Nahuel Moreyra

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Personal information

Social/Scientific Networks

About me

I have a BSc. in Bioinformatics and a Ph.D. in Evolutionary Biology. I am passionate about next generation sequencing technologies, omic sciences and programming to answer biological and ecological questions. I currently hold a postdoctoral position at IEGEBA and FuEDEI. In this project I apply comparative genomic methodologies to investigate ecological speciation in cactophilic moths of the genus Cactoblastis.

Languages

Education

Name Institution Project title Start Date End Date
Postdoctoral Studies Instituto de Ecología, Genética y Evolución de Buenos Aires (IEGEBA, UBA-CONICET) and Fundación para el Estudio de Especies Envasivas (FuEDEI). Ciudad de Buenos Aires, Argentina. Comparative genomics of cactophilic moths of the genus Cactoblastis. 2021 Present
Ph.D. in Biological Sciences Facultad de Ciencias Exactas y Naturales (FCEyN), Universidad de Buenos Aires (UBA). Ciudad de Buenos Aires, Argentina. Genome assembly and comparative analysis of the species D. borborema, D. antonietae y D. koepferae (Drosophila buzzatii cluster, repleta group). 2015 2020
BSc. in Bioinformatics Facultdad de Ingeniería (FI), Universidad Nacional de Entre Ríos (UNER). Oro Verde, Entre Rios, Argentina. Deconvolution of ELISPOT T-cell responses against HIV using immunoinformatic screening methods. 2008 2014

Research Scholarships

Description + Funding Project title Place of Work Start Date End Date
Ph.D. scholarship (Type I) - Agencia Nacional de Promoción Científica y Tecnológica (ANPCyT) Genome assembly of four South American cactophilic species belonging the Drosophila buzzatii* cluster IEGEBA 2015 2018
Short-term scholarship of DEANN Project “Marie Curie Actions - International Research Staff Exchange Scheme (IRSES)” financed by the European Commision. Identification and description of transponsable elements families in stressful cactophilic Drosophila genomes. Gonzalez Lab, Institut de Biologia Evolutiva (IBE), Barcelona, Cataluña, Spain. 2016 2016
Short-term Internship - Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) and ANPCyT Collaboration under the project “Genome assembly of four South American cactophilic species belonging the Drosophila buzzatii cluster”. Matzkin Lab, University of Arizona (UA), Tucson, United States (US) 2018 2018
Ph.D. Scholarship (Type II) - CONICET Genome assembly of four South American cactophilic species belonging the Drosophila buzzatii cluster IEGEBA 2018 2021
Postdoctoral Scholarship - CONICET Genome assembly of four South American cactophilic species belonging the Drosophila buzzatii cluster IEGEBA and FuEDEI 2021 2024

Mentoring

Position Student Studies Thesis Institution Start Date End Date
Director Ailin Glagovsky BSc. in Biotechnology Evolutionary analysis of the alcohol dehydrogenase protein family in the Drosophila buzzatii cluster (repleta group). Facultad de Bioquímica, Química y Farmacia (FBQF), Universidad Nacional de Tucumán (UNT) 2022 Present

Teaching Experience

Position Course Semester Institution Start Date End Date
Professor Health information systems (Technical and tertiary education) Annual Instituto de Formación Técnica Superior N° 7 (IFTS7) 2020 Present
Professor Informatics (Technical and tertiary education) 1st Instituto de Formación Técnica Superior N° 7 (IFTS7) 2020 Present
Professor Bioinformatics (undergraduate course) 2nd Universidad Favaloro (UF) 2018 2022
Invited teacher Evolutionary and Populational Genomics (post- and undergraduate course) 1st (90hrs) Departamento de Ecología, Genética y Evolución (EGE), (FCEyN-UBA 2018 2020
Teacher Programming in Python for Biology (workshop for undergraduate students) 2nd (32hrs) Universidad Favaloro (UF) 2018 2020
Invited teacher Human Population Genomics and diseases (postgraduate course) 1st (90hrs) Departamento de Ecología, Genética y Evolución (EGE), (FCEyN-UBA 2016 2017
Mentor Student-to-student mentoring Annual Facultad de Ingeniería (FI), Universidad Nacional de Entre Ríos (UNER) 2018 2020

Publications, preprints and drafts

  • Hasson E*, Moreyra NN (2023). Moscas y cactus: un sistema-modelo para el estudio del papel de los saltos de planta hospedadora en la diversificación. eVOLUCION, Boletín de la SESBE Vol. 17(1) Marzo 2023.
  • Mensch J*, Moreyra NN*, Hasson E (2023). Transcriptional responses of immature and mature females acclimated under the same low temperature provides insights into cold tolerance of cactophilic Drosophila buzzatii. In preparation to be submitted to Genes.
  • Moreyra NN*, Almeida F, Allan C, Frankel N, Matzkin L, Hasson E (2022). Phylogenomics provides insights into the evolution of cactophily and host plant shifts adaptation in Drosophila. Molecular Phylogenetics and Evolution. 2023 Jan 1;178:107653.
  • Rondón JJ*, Moreyra NN, Pisarenco VA, Rozas J, Hurtado J and Hasson E (2022). Evolution of the odorant-binding protein gene family in Drosophila. Front. Ecol. Evol. 10:957247. doi: 10.3389/fevo.2022.957247
  • Moreyra NN*, Mensch J, Hurtado J, Almeida F, Laprida C, Hasson E (2019). What does mitogenomics tell us about the evolutionary history of the Drosophila buzzatii cluster (repleta group)? PLoS ONE 14(11): e0220676. https://doi.org/10.1371/journal.pone.0220676.
  • Shome S*, Parra RG, Fatima N, Monzon AM, Cuypers B, Moosa Y, Coimbra NDR, Assis J, Giner-Delgado C, Dönertaş HM, Cuesta-Astroz Y, Saarunya G, Allali I, Gupta S, Srivastava A, Kalsan M, Valdivia C, J Olguin-Orellana G, Papadimitriou S, Parisi D, Kristensen NP, Rib L, Guebila MB, Bauer E, Zaffaroni G, Bekkar A, Ashano E, Paladin L, Necci M, Moreyra NN, Rydén M, Villalobos-Solís J, Papadopoulos N, Rafael C, Karakulak T, Kaya Y, Gladbach Y, Dhanda SK, Šoštarić N, Alex A, DeBlasio D, Rahman F. (2019). Global network of computational biology communities: ISCB's Regional Student Groups breaking barriers. F1000Research, 8, ISCB Comm J-1574. https://doi.org/10.12688/f1000research.20408.1.
  • Cravero F*, Landaburu LU, Moreyra NN, Fenoy E, Franzotti CL, Lanzarotti E, Parra RG, Palopoli N, Monzon AM. 2nd Argentine Symposium of Young Bioinformatics Researchers (2SAJIB) organized by the ISCB-SC RSG-Argentina. PeerJ Preprints; 2018 Jan 4. https://doi.org/10.7287/peerj.preprints.3504v2
  • Parra RG*, Defelipe LA, Guzovsky AB, Monzón A, Cravero F, Mancini E, Moreyra NN, Padilla Franzotti CL, Revuelta MV, Freiberger MI, Gonzalez NH. Highlights of the 1st Argentine Symposium of Young Bioinformatics Researchers (1SAJIB) organized by the ISCB RSG-Argentina. https://peerj.com/preprints/2494v1/

Software development

Name Description Repository Date
BUSCO2Tree A Python pipeline that helps to build a phylogenetic tree using the BUSCO results over a group of species/genomes/proteomes/transcriptomes. https://github.com/niconm89/BUSCO2Tree 2023

Evaluation1

Student Thesis tile Date
Mateo Gallia Estudio metagenómico de los microorganismos asociados a la digestión anaerobia de efluentes y de sus interacciones 2019
Clementina Penna Estudios evolutivos de las proteínas de interacción entre gametas del género Panthera 2019
Nahuel Abel Escobedo Caracterización de cambios conformacionales en proteínas homoligoméricas 2019

Awards

Description Awarded by Place Date
Travel Fellowship to attend to the EMBO Practical Course “Bioinformatics and Genome Analyses”. European Molecular Biology Organization (EMBO) Fondazione Edmund Mach (FEM), San Michelle all'Adige, Trento, Italy. 2019
Travel Fellowship Award to attend to the ECCB2016. European Conference on Computational Biology (ECCB) The Hague, Netherlands. 2016
Fellowship Award “Jóvenes Profesionales TICs 2013”. ANPCyT Oro Verde, Entre Ríos, Argentina 2013

Participation in Funded Scientific Projects2

Role Title Type of funding Start Date End Date
Research assistant La vida en pausa: metabolismo y evolución de la diapausa reproductiva en Drosophila Grant PICT 2018-03716 2020 2022
Ph.D. fellow Mapeo por NGS del período refractario de la hembra de Drosophila, un carácter blanco de la selección sexual postcopulatoria Grant PICT 2016/0253 2017 2020
Ph.D. fellow Mapeo de caracteres complejos por introgresión fenotípica selectiva combinada con secuenciación paralela masiva: el caso de la morfología genital en Drosophila Grant PICT 2013/1121 2014 2017

Postgraduate Courses

Course Duration Institution Place Date
Introduction to ‘omics Research 6 months Harvard Catalyst Virtual 2020
Programming in Python 4 months (120 hs) Universidad de San Martin (UNSAM) Virtual 2020
EMBO Practical Course: Bioinformatics and Genome Analyses 2 weeks (110 hs) European Molecular Biology Organization (EMBO) and the Fondazione Edmund Mach (FEM) FEM, San Michelle all'Adige, Italy June 16 to 30, 2019
Cladistic Analysis and Molecular Phylogenies 4 months (120hs) Departamento de Ecología, Genética y Evolución (EGE), (FCEyN-UBA Ciudad de Buenos Aires, Argentina March 1 to June 16, 2018
Advanced Genomic Analysis: de novo genome assembly 4 days (32 hs) Instituto Nacional de Tecnología Agropecuaria (INTA) and the Earlham Institute (EI) INTA Castelar, William C. Morris, Provincia de Buenos Aires, Argentina December 18 to 21, 2017
Genomic Tools and Bioinformatic Analysis 3 days (24hs) Ornithology Congress of the Americas and the Harvad University Instituto Misionero de Biodiversidad (ImiBio), Puerto Iguazú, Provincia de Misiones, Argentina August 6 to 8, 2017
Human genetics 10 days (80hs) Departamento de Fisiología, Biología Molecular y Celular (FBMC), (FCEyN-UBA Ciudad de Buenos Aires, Argentina July 3 to 14, 2017
Data Science in R: statistical basis 6 days (18hs) Instituto del Cálculo (IC), (FCEyN-UBA Ciudad de Buenos Aires, Argentina March 1 to 16, 2017
Genetics and Molecular Ecology 4 months (120hs) Departamento de Ecología, Genética y Evolución (EGE), (FCEyN-UBA Ciudad de Buenos Aires, Argentina March 1 to June 16, 2016
Human Population Genomics and Diseases 4 months (90hs) Departamento de Ecología, Genética y Evolución (EGE), (FCEyN-UBA Ciudad de Buenos Aires, Argentina August 1 to November 16, 2015
Introduction to Genomic Data Analysis Using HapMap and 1000 Genomes Projects (4th Edition) 5 days (40hs) Transmitting Science and the Instituto de Genética Veterinaria (IGEVET), CONICET La Plata, Provincia de Buenos Aires, Argentina August 10 to August 14, 2015

Other courses

Course Institution Place Date
Algorithms for DNA sequencing Coursera - Johns Hopkins University Virtual 2018
Python for Genomic Data Science Coursera - Johns Hopkins University Virtual 2017
Command Line Tools for Genomic Data Science Coursera - Johns Hopkins University Virtual 2016
Introduction to Relational DataBases with MySQL Workshop - RSG-Arg 4th Argentinean Conference on Computational Biology and Bioinformatics (4CAB2C).Bahía Blanca, Provincia de Buenos Aires, Argentina. 2015
Web Server programming Workshop - RSG-Arg Fundacion Instituto Leloir (FIL), Ciudad de Buenos Aires, Argentina. 2014
Programming in R Workshop - RSG-Arg 3rd Argentinean Conference on Computational Biology and Bioinformatics (3CAB2C), FI-[UNER](https://www.uner.edu.ar/, Oro Verde, Provincia de Entre Ríos, Argentina. 2012
Programming in Perl Workshop - RSG-Arg 3rd Argentinean Conference on Computational Biology and Bioinformatics (3CAB2C), FI-[UNER](https://www.uner.edu.ar/, Oro Verde, Provincia de Entre Ríos, Argentina. 2012

Technical Skills

Experince working in omic-related fields:

  • UNIX/Linux systems user
  • Experience working in HCP servers.
  • High-throuput sequencing data QC and curation (single-end, pair-ends, mate-pairs and long reads)
  • Repeat library generation and Transposable Element annotation
  • Genome assembly and annotation
  • Gene annotation curation (e.g. Apollo)
  • Orthology search/prediction
  • Management of genomic files such as gff, fasta, bed and related formats
  • Phylogenomics: phylogeny reconstruction and divergence time estimation
  • Molecular evolution analysis
  • Transcriptome assembly
  • Differential expresion analysis
  • Sequencing Experimental Design

Programming Languajes and Frameworks:

  • Python
  • Bash
  • R
  • AWK
  • Perl
  • C++ (bassic)

Other Knowledge:

  • Collaborative work on GitHub and GitLab

Educational Organizations and Voluntary Work

  • 2014 – Present. Regional Student Group Argentina (RSG-Arg)
    • The RSG is a group of students and young researchers in Bioinformatics and Computational Biology, that depends on the International Society of Computational Biology (ISCB) Student Council (SC.
    • Roles: Academic Advisor (2019 – Present); President (2018 – 2019); Secretary (2017); Financial Director (2016); Collaborator (2014 – 2015).

Participation in Conferences and Symposia

Event Participation Organizer Place Date
Biodiversity Genomics 2022 Conference (BG2022) Attendance BG2022 Virtual Session 2022
1st-7th Argentine Symposium of Young Researchers in Bioinformatics (SAJIB). Organizer Regional Student Group Argentina (RSG-Arg) Virtual Session 2016-2022
1st Latin American Congress on Evolution (CLEVOL) Oral presentation: Moreyra N., Ameida F., Hasson E.; Origin of cactophyly and functional genomic analysis of host plant use specialization the repleta group (genus Drosophila). Sociedad Argentina de Biología Evolutiva (SABE), Sociedad Chilena de Evolución (SOCEVOL) and Asociación Colombiana de Evolución (COLEVOL) Virtual Session 2021
II Reunión Argentina de Biología Evolutiva. Oral presentation: Moreyra N., Mensch J., Hurtado J., Ameida F., Laprida C., Hasson E.; What does mitogenomics tell us about the evolutionary history of the Drosophila buzzatii? Sociedad Argentina de Biología Evolutiva (SABE) FCEyN-UBA 2019
EMBO Practical Course: Bioinformatics and Genome Analyses. Poster: Moreyra NN., Mensch J., Hurtado J., Hasson E.; Tracing the evolutionary history of the Drosophila buzzatii cluster. European Molecular Biology Organization (EMBO) FEM, San Michelle all'Adige, Italy 2019
International Conference “Evolution and Ecology: The Cactophilic Drosophila Model System” Poster: *Moreyra NN.**, Mensch J., Hurtado J., Hasson E.; Comparative mitogenomic analysis of the Drosophila buzzatii cluster. Journal of Heredity El Pedregal Nature Logde and Resort, Los Alamos, Sonora, Mexico. 2018
15th European Conference on Computational Biology (ECCB2016). Poster: Moreyra NN., Mensch J., Hurtado J., Hasson E. Differential expression analysis of cold tolerance adaptation by RNA-seq de novo approach. European Conference on Computational Biology (ECCB) The Hague, Netherlands. 2016
6th Argentinian Conference on Bioinformatics and Computational Biology (6CAB2C). Poster: Moreyra NN., Mensch J., Hurtado J., Hasson E. Initial differential expression analysis of diapause in Argentinean D. buzzatii by RNA-seq de novo approach. Asociación Argentina de Bioinformática y Biología Computacional (A2B2C) Bahía Blanca, Provincia de Buenos Aires, Argentina. 2015
VI Latin American Conference on Biomedical Engineering (CLAIB). Oral Presentation: Moreyra NN., Brunner M., Metz S., Pais C. Cellular automata model approach for the study of the impact of social relationships on eating habits of adolescents of school age. Consejo Regional de Ingeniería Biomédica para América Latina Paraná, Entre Ríos, Argentina. 2014
IV Argentinean Conference on Computational Biology and Bioinformatics (4CAB2C). Poster: Moreyra NN., Nielsen M. Deconvoluting T cell HIV ELISPOT responses using immunoinformatics screening methods. Asociación Argentina de Bioinformática y Biología Computacional (A2B2C) Rosario, Provincia de Santa Fe, Argentina. 2013
3rd Argentinean Conference on Computational Biology and Bioinformatics (3CAB2C). Attendant Asociación Argentina de Bioinformática y Biología Computacional (A2B2C) Oro Verde, Provincia de Entre Ríos, Argentina. 2012
1st Argentinean Conference on Computational Biology and Bioinformatics (CAB2C). Attendant Asociación Argentina de Bioinformática y Biología Computacional (A2B2C) Bernal, Provincia de Buenos Aires, Argentina. 2010

Memberships

  • 2016 - 2019. International Society of Computational Biology (ISCB).

Footnotes

  1. By April 2022, all the items correspond to thesis evaluations of students that obtained a BSc. in Biological Sciences from the Universidad Favaloro (UF).

  2. All grants were funded by the Fondo para la Investigación Científica y Tecnológica (FONCYT).

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