Aquí aparecen todas las tablas del Anexo con su correspondiente pie de figura, a excepción de las Tabla 6 y 7 debido al volumen de las mismas que únicamente se han adjuntado en formato Excel, y sólo se muestra su pie de figura.
Tabla 1. Datos de muestreo y resultados del análisis de las muestras utilizadas en el estudio. La tabla incluye información sobre el origen de la muestra, tipo de muestra, fecha de muestreo, valor Ct (obtenido a partir del análisis del gen N), concentración (expresada en copias de genoma por litro) y la desviación estándar (SD) de la concentración. "ND" indica que los datos no están disponibles.
| ID Muestra | Origen de la muestra | Tipo de muestra | Fecha de muestreo | Ct1_gen_N1 | Ct2_gen_N1 | Concentración (gc/L) | SD |
|---|---|---|---|---|---|---|---|
| EVOG1 | Hospital General Universitario de Valencia | Agua residual compuesta 24h | 14/06/2023 | 29.86 | 30.23 | 1.13E+06 | 2.77E+05 |
| EVOG2 | Hospital General Universitario de Valencia | Agua residual simple | 06/09/2023 | 32.34 | 32.15 | 7.83E+05 | 2.22E+05 |
| EVOG3 | Hospital General Universitario de Valencia | Agua residual simple | 13/11/2023 | 30.17 | 29.57 | 1.33E+06 | 3.90E+05 |
| EVOG4 | Hospital General Universitario de Valencia | Agua residual simple | 08/01/2024 | 31.46 | ND | 5.05E+05 | 1.08E+05 |
| EVOG5 | Hospital General Universitario de Valencia | Agua residual simple | 10/01/2024 | 31.5 | 31.82 | 4.69E+05 | 1.73E+05 |
| EVOG6 | Hospital General Universitario de Valencia | Agua residual simple | 12/01/2024 | 32.05 | 31.95 | 2.99E+05 | 4.96E+04 |
| EVOG7 | Hospital General Universitario de Valencia | Agua residual simple | 15/01/2024 | 30.98 | 30.85 | 5.25E+05 | 6.40E+04 |
| EVOG8 | Hospital General Universitario de Valencia | Agua residual compuesta 24h | 18/01/2024 | 32.5 | 32.08 | 2.58E+05 | 6.07E+04 |
| EVOG9 | Hospital General Universitario de Valencia | Agua residual simple | 19/01/2024 | 33.73 | 33.9 | 2.60E+05 | 4.29E+03 |
| EVOG10 | Hospital General Universitario de Valencia | Agua residual simple | 24/01/2024 | 32.95 | 32.89 | 2.24E+05 | 8.59E+04 |
| EVOG11 | Hospital General Universitario de Valencia | Agua residual simple | 26/01/2024 | 31.64 | 31.8 | 2.97E+05 | 2.97E+05 |
| EVOG12 | Hospital General Universitario de Valencia | Agua residual simple | 29/01/2024 | 32.6 | 32.52 | 3.09E+05 | 3.09E+05 |
| EVOG13 | Hospital General Universitario de Valencia | Agua residual simple | 31/01/2024 | 32.69 | 32.54 | 3.27E+05 | 1.59E+05 |
| EVOG14 | Hospital General Universitario de Valencia | Agua residual simple | 02/02/2024 | 31.81 | 31.84 | 3.25E+05 | 5.09E+04 |
| EVOG15 | Hospital General Universitario de Valencia | Agua residual compuesta 24h | 06/03/2024 | 36.06 | 37.11 | 1.49E+04 | 4.74E+03 |
| EVOG16 | Hospital General Universitario de Valencia | Agua residual simple (congelada) | 17/05/2024 | 35.69 | 36.06 | 2.22E+04 | 2.57E+03 |
| PND149 | Depuradora Pinedo | Agua de la planta residual | 07/06/2023 | 34.99 | 35.76 | 3.11E+04 | 1.04E+04 |
| PND150 | Depuradora Pinedo | Agua de la planta residual | 21/06/2023 | 32.55 | 32.09 | 2.08E+05 | 4.21E+04 |
| PND151 | Depuradora Pinedo | Agua de la planta residual | 05/07/2023 | 32.93 | 32.81 | 1.46E+05 | 7.76E+03 |
| PND152 | Depuradora Pinedo | Agua de la planta residual | 19/07/2023 | 32.58 | 32.78 | 1.64E+05 | 1.46E+04 |
| PND153 | Depuradora Pinedo | Agua de la planta residual | 02/08/2023 | 35.53 | 35.58 | 2.70E+04 | 5.99E+02 |
| PND154 | Depuradora Pinedo | Agua de la planta residual | 16/08/2023 | 30.87 | 29.25 | 1.49E+06 | 1.07E+06 |
| PND155 | Depuradora Pinedo | Agua de la planta residual | 30/08/2023 | 34.28 | 33.28 | 8.63E+04 | 3.71E+04 |
| PND156 | Depuradora Pinedo | Agua de la planta residual | 13/09/2023 | 34.08 | 34.02 | 6.94E+04 | 1.85E+03 |
| PND157 | Depuradora Pinedo | Agua de la planta residual | 27/09/2023 | 30.8 | 30.91 | 5.16E+05 | 2.52E+04 |
| PND158 | Depuradora Pinedo | Agua de la planta residual | 11/10/2023 | 34.98 | 35.54 | 3.30E+04 | 8.11E+03 |
| PND159 | Depuradora Pinedo | Agua de la planta residual | 25/10/2023 | 33.31 | 32.87 | 1.28E+05 | 2.48E+04 |
| PND160 | Depuradora Pinedo | Agua de la planta residual | 08/11/2023 | 36.12 | 36.16 | 1.87E+04 | 3.32E+02 |
| PND161 | Depuradora Pinedo | Agua de la planta residual | 22/11/2023 | 34.05 | 34.34 | 6.36E+04 | 8.17E+03 |
| PND162 | Depuradora Pinedo | Agua de la planta residual | 29/11/2023 | 32.12 | 32.49 | 2.09E+05 | 3.42E+04 |
| PND163 | Depuradora Pinedo | Agua de la planta residual | 20/12/2023 | 33.73 | 33.7 | 8.56E+04 | 1.14E+03 |
| PND164 | Depuradora Pinedo | Agua de la planta residual | 17/01/2024 | 34.23 | 33.76 | 7.26E+04 | 1.50E+04 |
| PND165 | Depuradora Pinedo | Agua de la planta residual | 31/01/2024 | 31.7 | 31.67 | 3.06E+05 | 4.08E+03 |
| COV121245 | Hospital General Universitario de Valencia | Muestra clínica | 26/10/2023 | 22.56 | ND | ND | ND |
Tabla 2. Concentración de ADNc en ng/µL obtenida mediante cuantificación con Qubit después de la PCR. La tabla muestra las concentraciones de ADNc para cada una de las muestras tras la amplificación por PCR. Las concentraciones están expresadas en nanogramos por microlitro (ng/µL) y reflejan la cantidad de producto amplificado en cada reacción de PCR.
| Muestra | Concentración ng/µL Qubit |
|---|---|
| EVOG1 | 5.9 |
| EVOG2 | 4.8 |
| EVOG3 | 10.5 |
| EVOG4 | 4.65 |
| EVOG5 | 4.22 |
| EVOG6 | 4.96 |
| EVOG7 | 4.34 |
| EVOG8 | 7.86 |
| EVOG9 | 4.9 |
| EVOG10 | 7.33 |
| EVOG11 | 5.45 |
| EVOG12 | 5.23 |
| EVOG13 | 5.23 |
| EVOG14 | 6.34 |
| EVOG15 | 3.39 |
| PND149 | 6.15 |
| PND150 | 5.62 |
| PND151 | 5.59 |
| PND152 | 7.81 |
| PND153 | 7.83 |
| PND154 | 6.77 |
| PND155 | 4.23 |
| PND156 | 7.73 |
| PND157 | 5.21 |
| PND158 | 6.26 |
| PND159 | 6.49 |
| PND160 | 5.88 |
| PND161 | 6.91 |
| PND162 | 5.28 |
| PND163 | 7.54 |
| PND164 | 7.83 |
| PND165 | 8.62 |
| COV121245 | 17.8 |
Tabla 3. Datos de secuenciación y cobertura del genoma para cada muestra. La tabla muestra las características de las muestras analizadas, incluyendo el tipo de secuenciación realizada, el número total de lecturas obtenidas, las lecturas mapeadas y el porcentaje de cobertura del genoma tras el análisis informático. El genoma cubierto (%) se calcula combinando los datos de todas las ejecuciones disponibles para cada tipo de secuenciación.
| Muestra | Secuenciación | Lecturas totales | Lecturas Mapeadas | Genoma cubierto (%) |
|---|---|---|---|---|
| EVOG1 | Nanopore_Lib_1 | 64,449 | 722 | 61.67 |
| Nanopore_Lib_3 | 60,375 | 106 | ||
| Illumina_Run_1 | 350,196 | 243,542 | 93.12 | |
| EVOG2 | Illumina_Run_1 | 344,076 | 253,934 | 90.36 |
| EVOG3 | Nanopore_Lib_1 | 57,958 | 858 | 57.84 |
| Illumina_Run_1 | 281,548 | 21,248 | 73.28 | |
| EVOG4 | Illumina_Run_1 | 319,386 | 129,962 | 48.04 |
| Illumina_Run_2 | 345,082 | 236,869 | ||
| EVOG5 | Illumina_Run_1 | 323,934 | 183,709 | 64.78 |
| EVOG6 | Illumina_Run_1 | 335,886 | 61,539 | 30.93 |
| Illumina_Run_2 | 464,531 | 89,656 | ||
| EVOG7 | Illumina_Run_1 | 304,646 | 169,896 | 67.72 |
| EVOG8 | Nanopore_Lib_1 | 4,721 | 68 | 49.71 |
| Illumina_Run_1 | 360,531 | 20,271 | 36.39 | |
| Illumina_Run_2 | 362,548 | 74,941 | ||
| EVOG9 | Illumina_Run_1 | 393,522 | 3,002 | 26.48 |
| Illumina_Run_2 | 420,744 | 102,843 | ||
| EVOG10 | Nanopore_Lib_1 | 6,767 | 67 | 40.15 |
| Illumina_Run_1 | 285,686 | 81,296 | 68.43 | |
| Illumina_Run_2 | 369,432 | 122,002 | ||
| EVOG11 | Nanopore_Lib_1 | 5,431 | 103 | 42.71 |
| Illumina_Run_1 | 366,162 | 204,823 | 56.72 | |
| EVOG12 | Illumina_Run_1 | 324,868 | 156,264 | 69.64 |
| Illumina_Run_2 | 422,192 | 236,172 | ||
| EVOG13 | Illumina_Run_1 | 296,642 | 108,731 | 49 |
| Illumina_Run_2 | 426,038 | 223,645 | ||
| EVOG14 | Illumina_Run_1 | 336,688 | 140,756 | 55.24 |
| Illumina_Run_2 | 495,966 | 307,402 | ||
| EVOG15 | Illumina_Run_1 | 213,482 | 6,04 | 26.69 |
| Illumina_Run_2 | 366,814 | 35,192 | ||
| EVOG16 | Illumina_Run_2 | 405,626 | 2,214 | 3.93 |
| PND149 | Nanopore_Lib_1 | 42,121 | 397 | 60.62 |
| Illumina_Run_1 | 269,942 | 12,136 | 28.35 | |
| Illumina_Run_2 | 456,768 | 98,756 | ||
| PND150 | Nanopore_Lib_1 | 3,366 | 45 | 37.62 |
| Illumina_Run_1 | 326,724 | 91,122 | 35.25 | |
| Illumina_Run_2 | 413,044 | 164,413 | ||
| PND151 | Illumina_Run_1 | 359,436 | 159,222 | 38.82 |
| Illumina_Run_2 | 391,644 | 163,636 | ||
| PND152 | Nanopore_Lib_1 | 59,378 | 662 | 62.26 |
| Nanopore_Lib_3 | 36,301 | 215 | ||
| Illumina_Run_1 | 360,908 | 227,221 | 90.63 | |
| PND153 | Nanopore_Lib_1 | 111,566 | 913 | 64.39 |
| Illumina_Run_1 | 305,582 | 163,585 | 53.45 | |
| PND154 | Nanopore_Lib_1 | 93,673 | 871 | 61.35 |
| Illumina_Run_1 | 392,704 | 258,084 | 73.09 | |
| PND155 | Illumina_Run_1 | 341,004 | 206,662 | 75.21 |
| Illumina_Run_2 | 435,572 | 354,199 | ||
| PND156 | Nanopore_Lib_1 | 79,866 | 749 | 59.05 |
| Illumina_Run_1 | 332,532 | 127,308 | 65.95 | |
| Illumina_Run_2 | 471,782 | 306,556 | ||
| PND157 | Illumina_Run_1 | 692,086 | 228,061 | 59.64 |
| PND158 | Nanopore_Lib_2 | 469 | 37 | 30.96 |
| Illumina_Run_1 | 341,024 | 137,244 | 60.14 | |
| Illumina_Run_2 | 540,654 | 258,442 | ||
| PND159 | Nanopore_Lib_2 | 244 | 49 | 30.62 |
| Illumina_Run_1 | 324,964 | 170,247 | 55.73 | |
| Illumina_Run_2 | 456,228 | 276,657 | ||
| PND160 | Nanopore_Lib_2 | 582 | 90 | 43.66 |
| Illumina_Run_1 | 369,874 | 208,046 | 55.10 | |
| PND161 | Nanopore_Lib_2 | 928 | 52 | 43.69 |
| Illumina_Run_1 | 620,006 | 351,855 | 62.75 | |
| PND162 | Illumina_Run_1 | 286,626 | 146,873 | 72.87 |
| Illumina_Run_2 | 490,272 | 368,198 | ||
| PND163 | Nanopore_Lib_3 | 43,198 | 164 | 60.58 |
| Illumina_Run_1 | 371,456 | 256,985 | 90.96 | |
| PND164 | Nanopore_Lib_3 | 13,75 | 159 | 60.54 |
| Illumina_Run_1 | 389,975 | 277,999 | 86.94 | |
| PND165 | Nanopore_Lib_3 | 32,082 | 137 | 54.02 |
| Illumina_Run_1 | 382,416 | 279,323 | 93.98 | |
| COV121245 | Nanopore_Lib_2 | 179,581 | 170,327 | 99.43 |
| Nanopore_Lib_3 | 34,077 | 21,794 |
Tabla 4. Listado de los diferentes linajes presentes en cada una de las muestras secuenciadas con la plataforma Illumina, junto con su abundancia relativa sobre 1. También se incluye la fecha de muestreo correspondiente para cada muestra.
| Muestra | Linaje | Abundancia | Fecha |
|---|---|---|---|
| EVOG1 | XBB.1.5 | 1 | 14/06/2023 |
| EVOG2 | XBB.1.5 | 0.9995 | 06/09/2023 |
| EVOG3 | XBB.1.5 | 1 | 13/11/2023 |
| EVOG4 | BA.2.3.21 | 0.9972 | 08/01/2024 |
| EVOG5 | BA.2.19 | 0.9250 | 10/01/2024 |
| EVOG5 | BA.2.10.1 | 0.0247 | 10/01/2024 |
| EVOG5 | BA.2.10 | 0.0247 | 10/01/2024 |
| EVOG5 | BA.2.10.3 | 0.0247 | 10/01/2024 |
| EVOG6 | BA.2.1 | 0.3318 | 12/01/2024 |
| EVOG6 | BA.2.10.1 | 0.2216 | 12/01/2024 |
| EVOG6 | BA.2.10.3 | 0.2216 | 12/01/2024 |
| EVOG6 | BA.2.10 | 0.2216 | 12/01/2024 |
| EVOG7 | BA.2.1 | 0.9978 | 15/01/2024 |
| EVOG8 | BA.2.3.21 | 0.4987 | 18/01/2024 |
| EVOG8 | XBB.1.5 | 0.2299 | 18/01/2024 |
| EVOG8 | XBB.1.4 | 0.1350 | 18/01/2024 |
| EVOG8 | XBB.1.4.1 | 0.1350 | 18/01/2024 |
| EVOG9 | BA.2.1 | 0.9949 | 19/01/2024 |
| EVOG9 | BA.5.1.4 | 0.0017 | 19/01/2024 |
| EVOG10 | BA.2.16 | 0.9996 | 24/01/2024 |
| EVOG11 | XAS | 0.9977 | 26/01/2024 |
| EVOG12 | BA.2.1 | 0.9966 | 29/01/2024 |
| EVOG12 | BA.2.19 | 0.0017 | 29/01/2024 |
| EVOG13 | BA.2.85 | 0.0996 | 31/01/2024 |
| EVOG13 | BA.2.10.1 | 0.0996 | 31/01/2024 |
| EVOG13 | BA.2.32 | 0.0996 | 31/01/2024 |
| EVOG13 | BA.2.40 | 0.0996 | 31/01/2024 |
| EVOG13 | BA.2.8 | 0.0996 | 31/01/2024 |
| EVOG13 | BA.2.24 | 0.0996 | 31/01/2024 |
| EVOG13 | BA.2.10 | 0.0996 | 31/01/2024 |
| EVOG13 | BA.2.1 | 0.0996 | 31/01/2024 |
| EVOG13 | BA.2.27 | 0.0996 | 31/01/2024 |
| EVOG13 | BA.2.5 | 0.0996 | 31/01/2024 |
| EVOG14 | BA.2.35 | 0.0384 | 02/02/2024 |
| EVOG14 | BA.2.39 | 0.0384 | 02/02/2024 |
| EVOG14 | BA.2.9.2 | 0.0384 | 02/02/2024 |
| EVOG14 | BA.2.45 | 0.0384 | 02/02/2024 |
| EVOG14 | BA.2.40.1 | 0.0384 | 02/02/2024 |
| EVOG14 | BA.2.16 | 0.0384 | 02/02/2024 |
| EVOG14 | BA.2.7 | 0.0384 | 02/02/2024 |
| EVOG14 | BA.2.9 | 0.0384 | 02/02/2024 |
| EVOG14 | BA.2.6 | 0.0384 | 02/02/2024 |
| EVOG14 | BA.2.69 | 0.0384 | 02/02/2024 |
| EVOG14 | BA.2.33 | 0.0384 | 02/02/2024 |
| EVOG14 | BA.2.34 | 0.0384 | 02/02/2024 |
| EVOG14 | BA.2.28 | 0.0384 | 02/02/2024 |
| EVOG14 | BA.2.40 | 0.0384 | 02/02/2024 |
| EVOG14 | BA.2.62 | 0.0384 | 02/02/2024 |
| EVOG14 | BA.2.63 | 0.0384 | 02/02/2024 |
| EVOG14 | BA.2.8 | 0.0384 | 02/02/2024 |
| EVOG14 | BA.2.64 | 0.0384 | 02/02/2024 |
| EVOG14 | BA.2.24 | 0.0384 | 02/02/2024 |
| EVOG14 | BA.2.3 | 0.0384 | 02/02/2024 |
| EVOG14 | BA.2.1 | 0.0384 | 02/02/2024 |
| EVOG14 | BA.2.27 | 0.0384 | 02/02/2024 |
| EVOG14 | BA.2.56 | 0.0384 | 02/02/2024 |
| EVOG14 | BA.2.65 | 0.0384 | 02/02/2024 |
| EVOG14 | BA.2.5 | 0.0384 | 02/02/2024 |
| EVOG14 | BA.2 | 0.0384 | 02/02/2024 |
| EVOG15 | BA.2.9.2 | 0.8182 | 06/03/2024 |
| EVOG15 | DD.1 | 0.0897 | 06/03/2024 |
| EVOG15 | BA.3 | 0.0893 | 06/03/2024 |
| EVOG16 | XAY | 0.500 | 17/05/2024 |
| EVOG16 | XAY.1 | 0.500 | 17/05/2024 |
| PND149 | XBB.2.2 | 0.1248 | 07/06/2023 |
| PND149 | XBB.2.1 | 0.1248 | 07/06/2023 |
| PND149 | XBB.4.1 | 0.1248 | 07/06/2023 |
| PND149 | XBB.5 | 0.1248 | 07/06/2023 |
| PND149 | XBB.2 | 0.1248 | 07/06/2023 |
| PND149 | XBB.1 | 0.1248 | 07/06/2023 |
| PND149 | XBB.4 | 0.1248 | 07/06/2023 |
| PND149 | XBB | 0.1248 | 07/06/2023 |
| PND150 | XBB.1.5 | 0.4998 | 21/06/2023 |
| PND150 | XBB.1.4 | 0.4998 | 21/06/2023 |
| PND151 | XBB.1.4 | 0.4994 | 05/07/2023 |
| PND151 | XBB.1.4.1 | 0.4994 | 05/07/2023 |
| PND152 | XBB.1.5 | 1 | 19/07/2023 |
| PND153 | XBB.1.4.1 | 0.3318 | 02/08/2023 |
| PND153 | XBB.1.5 | 0.3318 | 02/08/2023 |
| PND153 | XBB.1.4 | 0.3318 | 02/08/2023 |
| PND153 | XBB.1.6 | 0.0024 | 02/08/2023 |
| PND153 | XBB | 0.0010 | 02/08/2023 |
| PND153 | XBB.4 | 0.0010 | 02/08/2023 |
| PND154 | XBB.1.7 | 0.7468 | 16/08/2023 |
| PND154 | XBB.1.5 | 0.1818 | 16/08/2023 |
| PND154 | XBB.1 | 0.0714 | 16/08/2023 |
| PND155 | XBB.1.5 | 0.4564 | 30/08/2023 |
| PND155 | XBK | 0.0054 | 30/08/2023 |
| PND156 | XBB.1.4 | 0.9983 | 13/09/2023 |
| PND156 | XBB.1 | 0.5366 | 30/08/2023 |
| PND157 | XBB.1 | 0.9983 | 27/09/2023 |
| PND158 | XBB.1.5 | 0.6665 | 11/10/2023 |
| PND158 | XBB.1 | 0.1665 | 11/10/2023 |
| PND158 | XBB.1.3 | 0.1665 | 11/10/2023 |
| PND159 | XBB.1.5 | 0.6111 | 25/10/2023 |
| PND159 | XBB.1 | 0.3889 | 25/10/2023 |
| PND160 | XBB.1 | 0.4999 | 08/11/2023 |
| PND160 | XBB.1.4 | 0.4999 | 08/11/2023 |
| PND161 | XBB.1.5 | 0.4930 | 22/11/2023 |
| PND161 | XBB.1.6 | 0.2531 | 22/11/2023 |
| PND161 | XBB | 0.2524 | 22/11/2023 |
| PND162 | BA.2.57 | 0.2379 | 29/11/2023 |
| PND162 | BA.2.38 | 0.2379 | 29/11/2023 |
| PND162 | BA.2.68 | 0.2379 | 29/11/2023 |
| PND162 | BA.2.3 | 0.0455 | 29/11/2023 |
| PND162 | BA.2.5 | 0.0455 | 29/11/2023 |
| PND162 | BA.2.1 | 0.0455 | 29/11/2023 |
| PND162 | BA.2.56 | 0.0455 | 29/11/2023 |
| PND162 | BA.2.27 | 0.0455 | 29/11/2023 |
| PND162 | BA.2 | 0.0455 | 29/11/2023 |
| PND162 | BA.2.10.1 | 0.0036 | 29/11/2023 |
| PND162 | BA.2.10 | 0.0036 | 29/11/2023 |
| PND162 | XBB.1.4 | 0.0022 | 29/11/2023 |
| PND163 | BA.2.1 | 0.8900 | 20/12/2023 |
| PND163 | XBB.1.3 | 0.0548 | 20/12/2023 |
| PND163 | XBB.1 | 0.0548 | 20/12/2023 |
| PND164 | BA.2.1 | 1 | 17/01/2024 |
| PND165 | BA.2.11 | 0.9970 | 31/01/2024 |
Tabla 5. Listado de los diferentes linajes presentes en cada una de las muestras secuenciadas con la plataforma Nanopore, junto con su abundancia relativa sobre 1. También se incluye la fecha de muestreo para cada muestra.
| Muestra | Linaje | Abundancia | Fecha |
|---|---|---|---|
| EVOG1 | XBB.1.4 | 0.20000000 | 14/06/2023 |
| EVOG1 | XBB.2 | 0.20000000 | 14/06/2023 |
| EVOG1 | XBB.1 | 0.20000000 | 14/06/2023 |
| EVOG1 | XBB | 0.20000000 | 14/06/2023 |
| EVOG1 | XBB.4 | 0.20000000 | 14/06/2023 |
| EVOG3 | XBB.4 | 0.20000000 | 13/11/2023 |
| EVOG3 | XBB.1.4 | 0.20000000 | 13/11/2023 |
| EVOG3 | XBB.2 | 0.20000000 | 13/11/2023 |
| EVOG3 | XBB | 0.20000000 | 13/11/2023 |
| EVOG3 | XBB.1 | 0.20000000 | 13/11/2023 |
| EVOG11 | XBB.1.5 | 0.16666667 | 26/01/2024 |
| EVOG11 | XBB.1.4 | 0.16666667 | 26/01/2024 |
| EVOG11 | XBB.2 | 0.16666667 | 26/01/2024 |
| EVOG11 | XBB | 0.16666667 | 26/01/2024 |
| EVOG11 | XBB.1 | 0.16666667 | 26/01/2024 |
| EVOG11 | XBB.4 | 0.16666667 | 26/01/2024 |
| PND149 | XBB.2 | 0.24285725 | 07/06/2023 |
| PND149 | XBB.1 | 0.24285725 | 07/06/2023 |
| PND149 | XBB | 0.24285725 | 07/06/2023 |
| PND149 | XBB.4 | 0.24285725 | 07/06/2023 |
| PND149 | BA.2.38.1 | 0.00317456 | 07/06/2023 |
| PND149 | BA.2.12.1 | 0.00317456 | 07/06/2023 |
| PND149 | BA.2.76 | 0.00317456 | 07/06/2023 |
| PND149 | BA.2.79 | 0.00317456 | 07/06/2023 |
| PND149 | BA.2.12 | 0.00317456 | 07/06/2023 |
| PND149 | BA.2.38 | 0.00317456 | 07/06/2023 |
| PND149 | BA.2.73 | 0.00317456 | 07/06/2023 |
| PND149 | BA.2.68 | 0.00317456 | 07/06/2023 |
| PND149 | BA.2.37 | 0.00317456 | 07/06/2023 |
| PND152 | XBB.4 | 0.20000000 | 19/07/2023 |
| PND152 | XBB.1.5 | 0.20000000 | 19/07/2023 |
| PND152 | XBB.2 | 0.20000000 | 19/07/2023 |
| PND152 | XBB | 0.20000000 | 19/07/2023 |
| PND152 | XBB.1 | 0.20000000 | 19/07/2023 |
| PND153 | XBB.2 | 0.25000000 | 02/08/2023 |
| PND153 | XBB.1 | 0.25000000 | 02/08/2023 |
| PND153 | XBB | 0.25000000 | 02/08/2023 |
| PND153 | XBB.4 | 0.25000000 | 02/08/2023 |
| PND154 | XBB.4 | 0.25000000 | 16/08/2023 |
| PND154 | XBB.2 | 0.25000000 | 16/08/2023 |
| PND154 | XBB.1 | 0.25000000 | 16/08/2023 |
| PND154 | XBB | 0.25000000 | 16/08/2023 |
| PND156 | XBB.1.4 | 0.20000000 | 13/09/2023 |
| PND156 | XBB.2 | 0.20000000 | 13/09/2023 |
| PND156 | XBB.1 | 0.20000000 | 13/09/2023 |
| PND156 | XBB | 0.20000000 | 13/09/2023 |
| PND156 | XBB.4 | 0.20000000 | 13/09/2023 |
| PND158 | XBB.1.5 | 0.35708558 | 11/10/2023 |
| PND158 | XBB.1 | 0.21430481 | 11/10/2023 |
| PND158 | XBB.1.4 | 0.21430481 | 11/10/2023 |
| PND158 | XBB.2 | 0.21430481 | 11/10/2023 |
| PND159 | XBB.1.5 | 1 | 25/10/2023 |
| PND160 | XBB.1.5 | 1 | 08/11/2023 |
| PND161 | XBB.1.5 | 1 | 22/11/2023 |
| PND163 | XBB.1.4 | 1 | 20/12/2023 |
| PND164 | XBB.1.4 | 1 | 17/01/2024 |
| PND165 | XBB.1.4 | 1 | 31/01/2024 |
| COV121245 | XBB.1.5 | 1 | 26/10/2023 |
Tabla 6. Listado de mutaciones genéticas identificadas en las muestras analizadas con la plataforma Illumina. Las columnas incluyen la identificación de la muestra, la posición genómica, el nucleótido de referencia, el nucleótido alterado, el gen afectado, la expresión nucleotídica, la expresión aminoacídica resultante, y la abreviatura del cambio aminoacídico correspondiente.
Tabla 7. Listado de mutaciones genéticas identificadas en las muestras analizadas con la plataforma Nanopore. Las columnas incluyen la identificación de la muestra, la posición genómica, el nucleótido de referencia, el nucleótido alterado, el gen afectado, la expresión nucleotídica, la expresión aminoacídica resultante, y la abreviatura del cambio aminoacídico correspondiente.