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1.12

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@github-actions github-actions released this 19 Nov 16:56
· 31 commits to main since this release
b56bf1c

What's new (and important)

simulate linkedreads now supports and defaults to haplotagging barcodes

  • 84 million barcode options instead of 14m
  • support for barcodes of any length, not just the 10X 16bp
  • barcode sequencing error has been removed because you're ultimately interested in the linked read data, not the sequencing nuances

Internal

  • HaploSim.pl (formerly LRSIM_harpy.pl) focuses solely on creating linked reads from provided haplotypes
  • output names for simulate linkedreads more flexible now
  • leveraged parameters better in HaploSim.pl
  • Added haplotag_barcodes.py to auto-generate haplotag barcodes
  • inline to haplotagging conversion uses memory-efficient in-memory sqlite3 database
  • barcode validations for align ema and simulate linkedreads

Bugs fixed

  • [simulate linkedreads] barcode key generated as a fixed keymap, ensuring barcodes have same haplotag code between different haplotypes

What's Changed

Full Changelog: 1.11...1.12