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mention integrations in index.rst
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39 changes: 38 additions & 1 deletion docs/source/index.rst
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Expand Up @@ -9,7 +9,8 @@ Welcome to the SAENOPY Documentation
SAENOPY is a free open source 3D traction force microscopy software. Its material model is especially well suited for
tissue-mimicking and typically highly non-linear biopolymer matrices such as collagen, fibrin, or Matrigel.

It features a python package to use in scripts and an extensive graphical user interface.
It features a python package to use in scripts and an extensive graphical user interface. The userinferface also has
integrations for spheriods, fiber alignment and 2D traction force microscopy.

This migration immune cell demonstrated what scientific discoveries you can achieve with saenop:

Expand Down Expand Up @@ -57,6 +58,42 @@ Now you can start the user interface with:

``saenopy``

Integrations
------------

Aside from saenopy's main use or 3D traction force microscopy we provide in our interface
integrations to related methods to asses cellular forces.

Spheroid
~~~~~~~~
3D traction force microscopy on multicellular aggregates (so-called spheroids).

https://github.com/christophmark/jointforces

* Mark C., Grundy T., Strissel P., Böhringer D., Grummel N., Gerum R., Steinwachs J., Hack C., Beckmann M., Eckstein M., Strick R., O'Neill G., Fabry B. (2020)
`"Collective forces of tumor spheroids in three-dimensional biopolymer networks" <https://doi.org/10.7554/eLife.51912>`_.
In eLife 9:e51912. doi.org/10.7554/eLife.51912

Orientation
~~~~~~~~~~~

Use fiber alignment as a proxy for force if the material properties are not available.

https://github.com/davidbhr/CompactionAnalyzer

* Böhringer D., Bauer A., Moravec I., Bischof L., Kah D., Mark C., Grundy T.J., Görlach E., O’Neill G.M., Budday S. and Strissel P.L., 2023.
`"Fiber alignment in 3D collagen networks as a biophysical marker for cell contractility" <https://doi.org/10.1016/j.matbio.2023.11.004>`_.
Matrix Biology, 124, pp.39-48. doi.org/10.1016/j.matbio.2023.11.004

pyTFM
~~~~~
Analyze force generation and stresses in cell colonies and confluent cell layers growing on a 2 dimensional surface.

https://github.com/fabrylab/pyTFM

* Bauer A., Prechová M., Fischer L., Thievessen I., Gregor M., & Fabry B. (2021).
`"pyTFM: A tool for traction force and monolayer stress microscopy" <https://doi.org/10.1371/journal.pcbi.1008364>`_.
PLoS computational biology, 17(6), e1008364. doi.org/10.1371/journal.pcbi.1008364

Citing Saenopy
--------------
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2 changes: 1 addition & 1 deletion saenopy/gui/orientation/gui_orientation.py
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Expand Up @@ -202,7 +202,7 @@ def __init__(self, parent=None):
with QtShortCuts.QHBoxLayout():
self.edge = QtShortCuts.QInputString(None, "edge", "40", type=int, settings=settings, settings_key="orientation/edge", tooltip="How many pixels to cut at the edge of the image.")
QtWidgets.QLabel("px").addToLayout()
self.max_dist = QtShortCuts.QInputString(None, "max_dist", "None", type=int, settings=settings, settings_key="orientation/max_dist", tooltip="Optional: specify the maximal distance around the cell center")
self.max_dist = QtShortCuts.QInputString(None, "max_dist", "None", type=int, settings=settings, settings_key="orientation/max_dist", tooltip="Optional: specify the maximal distance around the cell center", none_value=None)
QtWidgets.QLabel("px").addToLayout()

with QtShortCuts.QHBoxLayout():
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