This version has been developed related to the manuscript found here: Handels et al. [2024] https://doi.org/10.1016/j.jval.2024.07.009. In this manuscript we describe the new IPECAD open-source model framework (version 2) for the health-economic evaluation of early AD treatment and aim to apply it in 3 use cases for AD lecanemab treatment:
- Cross-validating an existing model with a similar structure.
- Cross-validating an existing model with a more complex structure.
- Assessing additional uncertainty scenarios.