SimTOST

The goal of SimTOST is to estimate the sample size sample size for a randomized, three-arm, parallel group phase I trial via simulation.

Installation

SimTOST is available on CRAN and can be installed by running the following code.

install.packages("SimTOST")

You can also install the development version of SimTOST from GitHub with:

# install.packages("devtools")
devtools::install_github("smartdata-analysis-and-statistics/SimTOST")

Example

The main features of this package is sampleSize function which can be used to calculate sample size for individual and multiple endpoints.

The example of using the functionality of this package can be found in these vignettes:

1. Sample size calculation of individual endpoint
2. Sample size calculation of multiple endpoints