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miRTarDS is a microRNA target interaction database, including 1,220,904 MTIs from miRTarbase, miRDB, miRWalk, involving 6,085 genes and 1,261 pre-miRNAs. The MTIs prediction achieved an F1 score of 0.889 in accurately distinguishing protein-level experimentally (western blot & reporter assay) validated MTIs and predicted MTIs.