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6 Example inputs

Torsten Pook edited this page Mar 20, 2019 · 1 revision
  • Parameter-name Default Other option:
  • prefilter FALSE TRUE
  • maf 0.00 Value between 0 and 0.5
  • equal_remove FALSE TRUE
  • window_sequence NULL (automatic generated)
  • window_size 20 Natural number (1,2,3,…)
  • merging_error 1 Natural number (1,2,3,…) - lower than window_size!
  • max_groups 0 to active: Natural number >= 2
  • bp_map NULL
  • window_anchor_gens NULL
  • blockinfo_mode 0 1 to minimize groups per window
  • at_least_one TRUE FALSE
  • multi_window_mode FALSE TRUE (use e.g. window_size=c(5,10,20,50))
  • blockinfo_mode_na FALSE TRUE (adjust merging_error ! )
  • na_snp_weight 2 Numeric value >0
  • na_seq_weight 0 Numeric value > 0
  • actual_snp_weight 5 Numeric value > 0
  • gap 10 Natural number (1,2,3,…)
  • min_share 0.975 Value between 0.5 and 1 (highly recommend to not use small values!
  • node_min 5 Natural number (1,2,3,…)
  • edge_min 5 Natural number (1,2,3,…)
  • multi_min 5 Natural number (1,2,3,…)
  • consider_nodes TRUE FALSE
  • consider_edge TRUE FALSE
  • consider_multi FALSE TRUE
  • subgroups NULL (automatic generated) List(1:500, 1:200, 1:300)
  • Subpopulation 1 in first 200 colums
  • Subpopulation 2 in last 300 colums
  • min_per_subgroup 0 Natural number (1,2,3,…) Only when one is explicitly interested in the overlap between both populations!
  • min_majorblock 5’000 Non-negativ-number (0,1,2,…)
  • min_majorblock_steps 4 Non-negativ-number (0,1,2,…)
  • min_similarity 0.99 Value between 0 and 1 (highly recommend to not use values below 0.9!
  • save_allblock TRUE FALSE
  • consider_all TRUE FALSE
  • merge_closeblock FALSE TRUE
  • max_diff_i 1 Non-negative-number (0,2,3,…)
  • max_diff_l 1 Non-negative-number (0,2,3,…)
  • off_lines 5 Natural number (1,2,3,…)
  • Weighting_length 1 Numeric value (<0 not recommended)
  • Weighting_size 1 Numeric value (<0 not recommended)
  • block_extending TRUE FALSE
  • snp_extending TRUE FALSE
  • max_extending_diff 1 Non-negative-number (0,2,3,…)
  • max_extending_diff_snp 0 Non-negative-number (1,2,3,…)
  • extending_ratio 20 Natural number (1,2,3,…) Avoid low values
  • extending_ratio_snp Inf Naturual number (1,2,3,…) Only change for long windows and high number of haplotypes in *blocks
  • off_node_addition FALSE TRUE
  • raster 5 Natural number (1,2,3,…)
  • recoding FALSE TRUE
  • recoding_notneeded FALSE TRUE
  • fast_compiler TRUE FALSE
  • intersect_func TRUE FALSE (base::intersect), usage of HaploBlocker::intersect requires that vector in an ascending *sequence of numbers
  • c_dhm_mode TRUE FALSE
  • big_output FALSE TRUE
  • target_coverage NULL Value between 0 and 1
  • max_iteration 10 Natural number (1,2,3,…)
  • min_step_size 25 Natural number (1,2,3,…)
  • target_stop 0.001 Value between 0 and 1 (recommend close to 0)
  • multi_window_mode FALSE TRUE;
  • Can be actived by using a vector for window_size; merging_error or min_share
  • adaptive_mode FALSE TRUE;
  • Sets window_size = c(5,10,20,50) and
  • Target_coverage = 0.9
  • developer_mode FALSE TRUE
  • parallel_window Inf Natural number – bigger than the biggest blocks one wants to identify
  • window_overlap 0 Natural number – nothing bigger than the size of the largest block is needed
  • window_cores 1 Natural number (2,3,4,…)
  • double_share 1 Value between 0 and 1 (nothing below 0.5 is recommended)
  • min_reduction_cross -Inf Non-negative-number (0,1,2,3,…)
  • min_reduction_neglet -Inf Non-negative-number (0,1,2,3,…)
  • early_remove FALSE TRUE
  • node_min_early NULL Natural number (1,2,3,…) – e.g. node_min / edge_min

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