Code to analyze evoked potentials from intraoperative DBS experiments, as well as paired pulse stimulation experiments in humans.
This repository contains MATLAB and R code to analyze the data from different sorts of DBS recordings, as well as paired pulse experiments. There exists analysis code for paired pulse experiments from both DBS and epilepsy patients.
The main script is master_script_betaStim.m, in the DBS_EP_PairedPulse folder, which calls other sub scripts and analysis functions. This generates time series plots of the different evoked potentials, as well as CSV files for further statistical analyses.
The R_code folder under DBS_EP_PairedPulse contains the R scripts required to fit linear mixed models and generate statistical plots after the data structure generated from the MATLAB code master_script_analyze_EP.m has been run. Each individual subject has various EP parameters that need to be set in prepare_EP_blocks.m.
screenBadChans is a boolean variable, which when enabled, allows for the visualization of each individual evoked potential to allow for manual rejection of bad trials.
After running the MATLAB analysis, the R analysis can be run.
R_data should contain the data files written out by the above MATLAB code.
R_config_files contains the individual subject configuration files for the R analysis scripts.
dose_response_R_script_trim_conditions.R produces the analysis contained within my thesis across all the subjects
baseline_variability_3d413.R produces the results for the patient of baseline variability under differing levels of anesthesia.
length_conditioning_a23ed.R analyzes the results from the different length conditioning sessions.
The folder DBS_EP_PairedPulse/intraoperative contains code to generate time series evoked potential plots during the running of experiments. intraop_DBS_patients is for DBS patients, while intraop_epilepsy_patients is for epilepsy patients.
The MATLAB script intraop_compare_EP_master_script.m needs to modified for each particular subject.
David J Caldwell, BSD-3 License