Vyper running straight in your Browser, thanks to pyodide & wasm.
Run it right away: https://jacqueswww.github.io/vyper-in-browser/
Download for offline use: https://github.com/jacqueswww/vyper-in-browser/archive/master.zip
To build your own Vyper wasm setup, see https://github.com/jacqueswww/pyodide