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fixes typos
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mikeyweigand committed Aug 27, 2021
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10 changes: 5 additions & 5 deletions mutations/MUTATIONS.md
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Expand Up @@ -40,23 +40,23 @@ Before adding, submitters are expected to confirm the validity of mutations to e
### How to contribute mutations

1. Fork this repository ([Do you need a GitHub account?](https://docs.github.com/en/get-started/signing-up-for-github/signing-up-for-a-new-github-account))
1. Copy `./import/mut_template.tsv` and name your file with an unique identifier using format:
[YYYYMMDD].[YourName].[0-9]{3}.tsv that can be used to link entries between the table and changelog (eg. `./20210812.Weigand.123.tsv`).
1. Copy `./import/mut_template.csv` and name your file with an unique identifier using format:
[YYYYMMDD].[YourName].[0-9]{3}.tsv that can be used to link entries between the table and changelog (eg. `./20210812.Weigand.123.csv`).
1. Enter mutation information according to the column descriptions below, entering 'NA' for any missing attributes except those marked as required. You may add multiple entries to this file.
1. Save your new mutation file to `./import`.
1. Commit your changes.
1. Submit a pull request.
1. Updated versions of `SCV2_mutations_latest.tsv` and `SCV2_mutations_latest.vcf` will be generated automatically when your pull request is approved.
1. Updated versions of `SCV2_mutations_latest.csv` and `SCV2_mutations_latest.vcf` will be generated automatically when your pull request is approved.

### Table column definitions

| Header | Description |
|----------------|--------------------------------|
|Chrom * |Name of the reference sequence [NC_045512.2](https://www.ncbi.nlm.nih.gov/nuccore/NC_045512.2)|
|Gene * |Annotated gene in the reference|
|Pos * |Base position in the reference|
|Position * |Base position in the reference|
|Reference * |Reference sequence |
|Mutation * |Mutation sequence change|
|Mutation * |Mutation sequence change (use '-' for deletion)|
|Description * |Human-readable description of mutation|
|Example |GenBank and/or SRA accession of example genome with confirmed mutation|
|Library |Primer set or library method information|
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2 changes: 1 addition & 1 deletion mutations/SC2_mutations_latest.csv
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Expand Up @@ -2,6 +2,6 @@ Chrom,Gene,Pos,Ref,Mut,Description,Example,Library,Platform,Analysis,Lineage,Sub
NC_045512,ORF3a,26158,GTTA,-,Frameshift due to 4nt deletion shifts stop codon upstream by 50nt,MT509959,NA,NA,NA,NA,Michael Weigand - TOAST,20210801
NC_045512,ORF3a,26152,G,T,Missense shifts stop codon upstream by 66nt,MW460877,NA,NA,NA,NA,Michael Weigand - TOAST,20210801
NC_045512,ORF7a,27577,C,T,Missense shifts stop codon upstream by 180nt,MW822023,NA,NA,NA,NA,Michael Weigand - TOAST,20210801
NC_045512,ORF7b,TT,-,Frameshift due to 2nt deletion shifts stop codon upstream by 34nt,MW653862,NA,NA,NA,NA,Michael Weigand - TOAST,20210801
NC_045512,ORF7b,27795,TT,-,Frameshift due to 2nt deletion shifts stop codon upstream by 34nt,MW653862,NA,NA,NA,NA,Michael Weigand - TOAST,20210801
NC_045512,ORF7b,27870,G,T,Missense shifts stop codon upstream by 15nt,MW447625,NA,NA,NA,NA,Michael Weigand - TOAST,20210801
NC_045512,ORF10,29642,C,T,Missense shifts stop codon upstream by 30nt,MT452576,NA,NA,NA,NA,Michael Weigand - TOAST,20210801

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