A Python implementation of the R package GeoDE (http://cran.r-project.org/web/packages/GeoDE/index.html)
$ pip install git+https://github.com/Maayanlab/geode.git
A geometrical Approach to Differential expression and gene-set enrichment.
Given expression data this package calculate a multivariate geometrical characterization of the differential expression and can also perform gene-set enrichment.
These functions is dependent on Numpy(http://www.numpy.org/) and Scikit-learn(http://scikit-learn.org/stable/)