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Kevlar version 0.2.0

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@standage standage released this 21 Jul 23:10
· 664 commits to master since this release

Kevlar release v0.2 adds new subcommands for read partitioning and variant calling, fixes a major bug with contig assembly, and introduces many minor fixes, improvements, and code refactoring.

Added

  • New subcommands
    • partition: group reads by shared interesting k-mers
    • localize: determine an assembled contig's location in the reference genome
    • call: align assembled contigs to reference and call variant
  • Documentation suite in docs/, hosted at https://kevlar.readthedocs.io
  • New third-party dependency ksw2 for computing alignments. Wrapped with Cython, which is a new development-time dependency (but not install or run time).
  • The pandas package is now a dependency, and pysam and networkx are now hard dependencies (rather than conditional).

Fixed

  • Bug with assembly when the order of a read pair was swapped and they had the opposite orientation (see #85).