decemedip: Cell type deconvolution of cell‑free DNA via Bayesian hierarchical modeling

The R package decemedip is a novel computational paradigm developed for inferring the relative abundances of cell types and tissues from tissue bulk or circulating cell-free DNA (cfDNA) measure by methylated DNA immunoprecipitation sequencing (MeDIP-Seq). This paradigm allows using reference data from other technologies such as microarray or WGBS.

Installation

You can install the development version of decemedip in R from GitHub with:

# install.packages("devtools")
devtools::install_github("nshen7/decemedip")

Citation

Manuscript is currently under development.